ArticleBioactive materials2021
Flexible electrical stimulation device with Chitosan-Vaseline® dressing accelerates wound healing in diabetes.
Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Making Sense of Electrical Stimulation: A Meta-analysis for Wound Healing.Annals of biomedical engineering · 2024Pooled it
- Effect of electrical stimulation on patients with diabetes-related ulcers: a systematic review and meta-analysis.BMC endocrine disorders · 2022Pooled it
- Functionalized bio-patches for intra-abdominal applications.iScience · 2026Review
- Multicomponent Peptide-MXene-Hyaluronic Acid Hydrogel as a Conductive Scaffold for Enhanced Fibroblast Proliferation and Migration Under Electrical Stimulation.Advanced healthcare materials · 2026Article
- Skin-mimetic bilayer hydrogel enhances spatiotemporal coordination of neuro-immune-vascular interactions to accelerate diabetic wound healing.Bioactive materials · 2026Article
- Restoration of endogenous electric fields with a glucose-powered symbiotic bioabsorbable bandage for diabetic wound healing.Science advances · 2026Article
- Wearable Battery-Free Electrotherapy of Smartsensors for Wound Healthcare.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Advances of piezoelectric biomaterials in bone defect repair: The role of direct and inverse piezoelectric effect.Journal of orthopaedic translation · 2026Review
- Comparative Evaluation of Single and Combination Pharmacologic and Device-Based Anti-scar Therapies in a Murine Linear Wound Model.Aesthetic plastic surgery · 2026Article
- Hydrogel-Flexible Electronics Integrated Platforms for Diabetic Wound Management.Materials (Basel, Switzerland) · 2026Review
- Electric field stimulation-responsive hydrogels for bone regeneration: from mechanisms to applications.Bone research · 2026Review
- A thermogalvanic cell dressing for smart wound monitoring and accelerated healing.Nature biomedical engineering · 2026Article
- An electroactive platform enabled by near-field communication for accelerating infected diabetic wound healing via directional electric field reshaping and immunomodulation.Regenerative biomaterials · 2026Article
- Harnessing stromal vascular fraction-based therapies for wound healing: Mechanisms, synergies, and clinical translation.Regenerative therapy · 2025Review
- Effects of electrode placement on electrical stimulation for wound healing.Scientific reports · 2025Article
- Additive Manufactured Magnetoelectric Wireless Retainer as the Periodontal Remodeler for Post-Orthodontic Tissue Reconstruction and Relapse-Inhibition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Natural Bioactive Compound-Integrated Nanomaterials for Diabetic Wound Healing: Synergistic Effects, Multifunctional Designs, and Challenges.Molecules (Basel, Switzerland) · 2025Review
- A carbon nanotube/pyrrolidonecarboxylic acid zinc sponge for programmed management of diabetic wounds: Hemostatic, antibacterial, anti-inflammatory, and healing properties.Materials today. Bio · 2025Article
- Electrical stimulation: a novel adjunct therapy for diabetic foot ulcers.Frontiers in clinical diabetes and healthcare · 2025Review
- Large Scale Ultrafast Manufacturing of Wireless Soft Bioelectronics Enabled by Autonomous Robot Arm Printing Assisted by a Computer Vision-Enabled Guidance System for Personalized Wound Healing.Advanced healthcare materials · 2025Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The healing process of diabetic wounds is typically disordered and prolonged and requires both angiogenesis and epithelialization. Disruptions of the endogenous electric fields (EFs) may lead to disordered cell migration. Electrical stimulation (ES) that mimics endogenous EFs is a promising method in treating diabetic wounds; however, a microenvironment that facilitates cell migration and a convenient means that can be used to apply ES are also required. Chitosan-Vaseline® gauze (CVG) has been identified to facilitate wound healing; it also promotes moisture retention and immune regulation and has antibacterial activity. For this study, we created a wound dressing using CVG together with a flexible ES device and further evaluated its potential as a treatment for diabetic wounds. We found that high voltage monophasic pulsed current (HVMPC) promoted healing of diabetic wounds
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.