Evidence map›Paper›PMID 32913876›Full record

ArticleOpen forum infectious diseases2020

An Adherence-Enhancing Program Increases Retention in Care in the Swiss HIV Cohort.

Susan Kamal, Tracy R Glass, Thanh Doco-Lecompte, Sophie Locher, Olivier Bugnon, Jean-Jacques Parienti, Matthias Cavassini, Marie P Schneider

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Susan KamalSchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.ORCID 0000-0001-9114-5667
Tracy R GlassClinical Statistics and Data Management Group, Swiss Tropical and Public Health Institute, Basel, Switzerland.ORCID 0000-0001-7075-9803
Thanh Doco-LecompteHIV Unit, Department of Internal Medicine, Geneva University Hospital, Geneva, Switzerland.
Sophie LocherSchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
Olivier BugnonSchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.ORCID 0000-0003-2249-1245
Jean-Jacques ParientiHospital Center University De Caen, Caen, France.
Matthias CavassiniInfectious Disease Service, Lausanne University Hospital, University of Lausanne, Lausanne Switzerland.ORCID 0000-0003-0933-7833
Marie P SchneiderSchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-7557-9278
University of Geneva · CHSwiss Tropical and Public Health Institute · CHUniversité de Caen Normandie · FRUniversity Hospital of Geneva · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study tested a theory-based adherence-enhancing intervention: the "Interprofessional Medication Adherence Program" (IMAP) to increase human immunodeficiency virus (HIV) retention in care.

methodsWe retrospectively compared our intervention center (intervention group [IG]) with a standard of care center (control group [CG]) both participating in the Swiss HIV Cohort Study between 2004 and 2012. Endpoints were defined as >6-month and >12-month gaps in care for intervals of care longer than 6 and 12 months without any blood draw. Inverse probability of treatment weights was used to adjust for differences between patients at the 2 centers. Viral failure was defined as ribonucleic acid ≥50 copies/mL after 24+ weeks on antiretrovirals.

resultsThe IG included 451 patients, CG 311. In the IG, 179 (40%) patients took part in the IMAP for a median of 27 months (interquartile range, 12-45). Gaps in care of ≥6 months were significantly more likely to happen in the CG versus IG (74.6% vs 57%,

conclusionsThis study, in a real-world setting, shows the effectiveness of the IMAP to reduce 6- and 12-month gaps in follow up among people with HIV. These results should be confirmed by studies in other settings.

Indexed as

adherence interventionantiretroviralsHIVinterprofessionalitymedication retention in care

Identifiers

PMID32913876
PMCPMC7473741
OpenAlexW3049151757

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.