Evidence map›Paper›PMID 32913680›Full record

ArticlePeerJ2020

Association analysis between chronic obstructive pulmonary disease and polymorphisms in circadian genes.

Guo Chen, Jingwei Zhang, Lijuan Zhang, Xuan Xiong, Dongke Yu, Yuan Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Circadian regulation of pulmonary disease: the importance of timing.Clinical science (London, England : 1979) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Guo Chen *Department of Geriatrics, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Cheng Du, China.
Jingwei Zhang *Department of Laboratory Medicine, Chengdu Second People's Hospital, Cheng Du, China.
Lijuan ZhangPersonalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Cheng Du, China.
Xuan XiongPersonalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Cheng Du, China.
Dongke YuPersonalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Cheng Du, China.
Yuan ZhangPersonalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Cheng Du, China.ORCID 0000-0001-8840-7531
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital · CNChengdu Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCircadian genes have been suggested to play an important role in lung pathology. However, it remains unknown whether polymorphisms of these genes are associated with chronic obstructive pulmonary disease (COPD). Here, we aimed to investigate the association of circadian genes polymorphisms with COPD in a case-control study of 477 COPD patient and 323 control Han Chinese persons.

methodsGenotyping assays were carried out for nine single nucleotide polymorphisms (SNPs) from five circadian genes (

resultsNo significant association was found in all SNP sites in overall subjects and no significant difference was found in age, sex, smoking status stratification analysis. DISCUSSION: The findings of this investigation indicated the effect of circadian genes polymorphisms on COPD susceptibility may only be small and possibly dependent on the subject factors, such as age and sex.

Indexed as

Case-control association studyChronic obstructive pulmonary diseaseCircadian genesGene polymorphismSusceptibility factors

Identifiers

PMID32913680
PMCPMC7456532
OpenAlexW3082687540

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.