Evidence map›Paper›PMID 32913573›Full record

ArticleJournal of clinical and experimental dentistry2020

Detection of mast cells in ameloblastomas and odontogenic keratocysts.

Erison-Santana Dos Santos, Richard-Ribeiro-Alonso de Andrade, Gerhilde-Callou Sampaio, Raisa-Queiroz Catunda, Emanuel-Sávio-de Souza Andrade

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Erison-Santana Dos SantosDDS, MSc Student, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
Richard-Ribeiro-Alonso de AndradeDDS, MSc, Assistant Professor, Department of Surgery and Oral Pathology, Pernambuco Dental School, University of Pernambuco, Camaragibe, Pernambuco, Brazil.
Gerhilde-Callou SampaioDDS, MSc, PhD, Adjunct Professor, Department of Surgery and Oral Pathology, Pernambuco Dental School, University of Pernambuco, Camaragibe, Pernambuco, Brazil.
Raisa-Queiroz CatundaDDS, MSc, PhD Candidate, Department of Medicine and Dentistry, School of Dentistry, University of Alberta - Edmonton, AB - Canada.
Emanuel-Sávio-de Souza AndradeDDS, MSc, PhD, Full Professor, Department of Surgery and Oral Pathology, Pernambuco Dental School, University of Pernambuco, Camaragibe, Pernambuco, Brazil.
Universidade de Pernambuco · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMCs (MCs) have been ascribed to mediating several diseases, including malignant neoplasms. These cells can play a role in angiogenesis, tissue remodeling and immune modulation and favor neoplasm progression. Despite the studies analyzing the contribution of MCs in odontogenic lesions, its biological behavior in ameloblastomas (AMBs) and odontogenic keratocysts (OKCs) remains unclear. This study aims to detect MCs in OKCs and AMBs and clarify the role of MCs in these lesions. MATERIAL AND

methodsA total of 40 odontogenic lesions were analyzed. This included 20 OKCs and 20 AMBs, 10 being the solid type and the other 10 being the unicystic type of AMB. All cases were histologically reviewed in hematoxylin-eosin. Clinical data, such as age, gender, location, size, radiographic presentation and, histologic patterns were collected from the clinical charts. The Mann-Whitney U test (MWU) was used verify the hypothesis, through inferential statistics. The level of significance used in the statistical test was 0.5%.

resultsMCs were observed in 60% of OKCs, and 35% of AMBs. The ratio of MCs observed in OKCs was 0.37, 0.48 in solid AMBs and 0.01 in unicystic AMBs. There was no significant difference between number of MCs in AMBs and OKCs, however, a significant difference was observed between solid and unicystic AMBs (

conclusionsMCs may play an important role in the biological behavior of AMBs and OKCs. However, in this study it was not possible to confirm the contribution of MCs in the biological behavior of these lesions and more studies are needed to clarify this relation.

Identifiers

PMID32913573
PMCPMC7474942
OpenAlexW3046305684

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.