ArticleJournal of clinical and experimental dentistry2020
Local complications associated with labial salivary gland biopsy for diagnosis of Sjögren's Syndrome: A retrospective cohort study.
Article in Journal of clinical and experimental dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease.Rheumatology (Oxford, England) · 2025Guideline
- Detecting Sjögren's Disease from Parotid Gland Ultrasound Radiomics.Rheumatology (Oxford, England) · 2026Article
- The diagnostic value and clinical relevance of salivary gland ultrasound in patients with highly suspected Sjögren's Disease: a prospective monocentric study.Arthritis research & therapy · 2025Article
- A non-invasive model for diagnosis of primary Sjogren's disease based on salivary biomarkers, serum autoantibodies, and Schirmer's test.Arthritis research & therapy · 2024Article
- Article
- Bedside labial salivary gland biopsy (LSGBx: Lip biopsy): An update for rheumatologists.Best practice & research. Clinical rheumatology · 2023Review
- Current Salivary Glands Biopsy Techniques: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2022Review
- Evaluation of CD20 in labial minor salivary gland biopsies in Sjogren's syndrome.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo describe local or systemic complications related to the labial salivary glands biopsy (LSGB) used as diagnostic tool for the diagnosis of Sjögren's Syndrome (SS). MATERIAL AND
methodsClinical databases from a cohort of patients, who underwent LSGB with provisional clinical diagnosis of Sjögren's Syndrome, were retrospectively reviewed. Pain, assessed by registering the intake of analgesic drugs in the first week following the biopsy, and any further relevant clinical information regarding complications after biopsy were recorded.
results50 patients received LSGB. 10 of them (9 women and 1 man) showed histopathological findings compatible with SS. Ten patient (20%) receiving labial biopsy developed local complications: three of them (6%) reported a sensory defect at the surgical site that lasted at most few weeks; three patients (6%) reported pain sensation needing the assumption of analgesic drugs, while one patient (2%) described a transient local burning sensation, which resolved in few days. Three patients (6%) showed cutaneous haematoma in the surgical area and two patients (4%) showed mild mucosal inflammation at the biopsy site.
conclusionsLSGB is associated with to few and mild complications and it is a useful tool in the diagnosis of SS. The complications usually resolved in few weeks after the biopsy.
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Registered trials
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