Evidence map›Paper›PMID 32913513›Full record

ArticleAmerican journal of translational research2020

Telocytes enhanced in vitro decidualization and mesenchymal-epithelial transition in endometrial stromal cells via Wnt/β-catenin signaling pathway.

Fei-Lei Zhang, Yue-Lin Huang, Xiao-Ye Zhou, Xue-Ling Tang, Xiao-Jun Yang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fei-Lei ZhangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu Province, PR China.
Yue-Lin HuangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu Province, PR China.
Xiao-Ye ZhouDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu Province, PR China.
Xue-Ling TangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu Province, PR China.
Xiao-Jun YangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu Province, PR China.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decidualization of endometrial stromal cells (ESCs) is essential for preparing endometrium for embryo implantation. Telocytes (TCs), a novel type of interstitial cell, exist in the female reproductive tract and participate in the pathophysiology of diseases. This study further investigates the hypothesis that TCs, a source of Wnt, modulates decidualization and MET in ESCs. We had observed differential expression of Wnt ligands in primary mice ESCs and TCs by qPCR. TCM-induced decidualization and MET was assessed in ESCs. Changes in markers for decidualization (cyclin-D3, desmin, d/tPRP), stromal cells (N-cadherin), epithelial cells (E-cadherin), and the Wnt/β-catenin pathway (β-catenin, FOXO1) were quantified by western blot and RT-PCR. β-catenin knockdown in ESCs decreased the degree of TCM-induced decidualization and MET, with significantly reversed expression profiles (

Indexed as

decidualizationendometrial stromal cells (ESCs)mesenchymal-epithelial transition (MET)Telocytes (TCs)Wnt/β-catenin signaling-pathway

Identifiers

PMID32913513
PMCPMC7476159
OpenAlexW3084980161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.