Evidence map›Paper›PMID 32913403›Full record

ArticleJournal of ginseng research2020

Effects of red ginseng on the elastic properties of human skin.

Moon Young Park, Se Jik Han, Donggerami Moon, Sangwoo Kwon, Jin-Woo Lee, Kyung Sook Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Moon Young ParkDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Se Jik HanDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Donggerami MoonDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Sangwoo KwonDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Jin-Woo LeeMedical Science Research Institute, Kyung Hee University Medical Center, Seoul, Republic of Korea.
Kyung Sook KimDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Kyung Hee University · KRKyung Hee University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRed ginseng contains components, including microelements, vitamins, essential oils, and fatty acids, that can be used in skincare to delay the aging process. We investigated the effects of red ginseng treatment on skin elasticity by assessing cellular stiffness and measuring collagen protein synthesis.

methodsHuman dermal fibroblasts were treated with red ginseng, and the resulting changes in stiffness were investigated using atomic force microscopy. Cytoskeletal changes and mRNA expression of biomarkers of aging, including that of procollagens I and VII, elastin, and fibrillin-1, were investigated. Collagen in a human skin equivalent treated with red ginseng was visualized via hematoxylin and eosin staining, scanning electron microscopy, and atomic force microscopy. RESULTS AND

conclusionThe stiffness of fibroblasts was significantly reduced by treatment with red ginseng concentrations of ≥ 0.8 mg/mL. The ratio of F-actin to G-actin decreased after treatment, which corresponded to a change in fibroblast stiffness. The storage modulus (

Indexed as

Atomic force microscopyCellular stiffnessCollagenRed ginsengSkin elasticity

Identifiers

PMID32913403
PMCPMC7471210
OpenAlexW2969965126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.