Evidence map›Paper›PMID 32913124›Full record

ArticleThe Journal of biological chemistry2020

Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection.

Inga Rimkute, Konrad Thorsteinsson, Marcus Henricsson, Victoria R Tenge, Xiaoming Yu, Shih-Ching Lin, Kei Haga, Robert L Atmar, Nils Lycke, Jonas Nilsson and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Norovirus-glycan interactions - how strong are they really?Biochemical Society transactions · 2022
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Inga RimkuteDepartment of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Konrad ThorsteinssonDepartment of Clinical Microbiology, Umeå University, Umeå, Sweden; Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden.
Marcus HenricssonWallenberg Laboratory, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Victoria R TengeDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Xiaoming YuDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Shih-Ching LinDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Kei HagaDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Robert L AtmarDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Nils LyckeDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jonas NilssonDepartment of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Laboratory of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.
Mary K EstesDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA. Electronic address: goran.larson@clinchem.gu.se.
Marta BallyDepartment of Clinical Microbiology, Umeå University, Umeå, Sweden; Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden.
Göran LarsonDepartment of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Laboratory of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address: mestes@bcm.edu.
Baylor College of Medicine · USUniversity of Gothenburg · SESahlgrenska University Hospital · SEUmeå University · SE

Funding

X-ray Crystallographic Studies on CalicivirusesP01AI057788 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI PRASAD, BIDADI VENKATARAM · 2004 to 2024
$34.4M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3M
Novel Platforms for Human Intestinal Enteroids: Matrix, Mechanics, and TopographyU19AI116497 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GRANDE-ALLEN, KATHRYN JANE · 2015 to 2025
$13.2M
NIAID NIH HHS P01 AI057788NIAID NIH HHS U19 AI116497NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

The molecular mechanisms behind infection and propagation of human restricted pathogens such as human norovirus (HuNoV) have defied interrogation because they were previously unculturable. However, human intestinal enteroids (HIEs) have emerged to offer unique

Indexed as

Virus AttachmentBlood Group AntigensCaliciviridae InfectionsGlycosphingolipidsHumansIntestinal MucosaNorovirusOrganoidsBlood Group AntigensGlycosphingolipidsceramidefucosyltransferaseglycerophospholipidglycolipid structureglycosphingolipidglycosylationhost-pathogen interactionhuman norovirusintestinal epitheliumintestineplus-stranded RNA virussphingolipidsphingomyelinviral replicationvirus entry

Identifiers

PMID32913124
PMCPMC7681023
OpenAlexW3086467150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.