Evidence map›Paper›PMID 32912972›Full record

SynthesisBMJ open2020

Prognostic value of red cell distribution width in patients undergoing percutaneous coronary intervention: a meta-analysis.

Donglai Bao, Gaojiang Luo, Fuqiang Kan, Xiaoyan Wang, Jinwei Luo, Changhao Jiang

Registry-linked trialAbstract readMeta-Analysis
In one paragraph

Synthesis in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07155395 (Relationship Between Inflammatory and Hematological Indices and Coronary Artery Disease Severity and Outcome Among Diabetic Patients Undergoing Primary Percutaneous Coronary Intervention), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07155395 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Relationship Between Inflammatory and Hematological Indices and Coronary Artery Disease Severity and Outcome Among Diabetic Patients Undergoing Primary Percutaneous Coronary Intervention

Typeobservational_patient_registrySponsorAssiut UniversityRan2025 to 2027Enrolled1,000ConditionsSTEMI, Diabete Mellitus
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Donglai BaoDepartment of Cardiovascular disease, Yiwu Central Hospital, Yiwu, China baodlyw01@tom.com.ORCID 0000-0001-6667-4049
Gaojiang LuoDepartment of Cardiovascular disease, Yiwu Central Hospital, Yiwu, China.
Fuqiang KanDepartment of Cardiovascular disease, Yiwu Central Hospital, Yiwu, China.
Xiaoyan WangDepartment of Cardiovascular disease, Yiwu Central Hospital, Yiwu, China.
Jinwei LuoDepartment of Cardiovascular disease, Yiwu Central Hospital, Yiwu, China.
Changhao JiangDepartment of Cardiovascular disease, Yiwu Central Hospital, Yiwu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the prognostic value of baseline red cell distribution width (RDW) in patients with coronary artery diseases (CADs) undergoing percutaneous coronary intervention (PCI) by conducting a meta-analysis.

designSystematic review and meta-analysis. DATA SOURCE: PubMed, Embase, Wanfang, CNKI and VIP databases were searched from their inceptions to 19 June 2019. ELIGIBLE CRITERIA: Studies investigating the value of baseline RDW for predicting all-cause mortality, cardiovascular mortality and major adverse cardiac events (MACEs) in patients with CAD undergoing PCI were included. DATA EXTRACTION AND SYNTHESIS: Two authors independently extracted the data and evaluated the methodological quality using the Newcastle-Ottawa Scale. STATA V.12.0 software was applied to produce the forest plots using a random-effect model.

resultsTwelve studies (13 articles) involving 17 113 patients were included and analysed. Comparison between the highest and lowest RDW category indicated that the pooled risk ratio (RR) was 1.77 (95% CI 1.32 to 2.37) for all-cause mortality, 1.70 (95% CI 1.25 to 2.32) for cardiovascular mortality and 1.62 (95% CI 1.21 to 2.18) for MACEs. The predictive effect of elevated RDW for all-cause mortality was stronger in the subgroup of patients without anaemia (RR 4.59; 95% CI 3.07 to 6.86) than with anaemia.

conclusionsThis meta-analysis indicated that elevated RDW was associated with higher risk of mortality and adverse cardiac events in patients with CAD undergoing PCI. The value of elevated RDW for predicting all-cause mortality appears to be stronger in patients without anaemia. RDW may be served as a promising prognostic biomarker in patients undergoing PCI.

Indexed as

Erythrocyte IndicesAgedFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionPrognosisStroke VolumeVentricular Function, Leftall-cause mortalitymajor adverse cardiac eventsmeta-analysispercutaneous coronary interventionred cell distribution width

Identifiers

PMID32912972
PMCPMC7485231

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.