Evidence map›Paper›PMID 32912887›Full record

ArticleBMJ case reports2020

Potassium losing, aldosterone producing adrenocortical carcinoma: a rare presentation.

Zahir S Hussain, Smitha S Rao, Wajith Z Hussain, Shikhil Puzhakkal

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zahir S HussainDepartment of Endocrine and Breast Surgery, Madras Medical College and Research Institute, Chennai, Tamil Nadu, India zahirdr@gmail.com.
Smitha S RaoDepartment of Endocrine and Breast Surgery, Madras Medical College and Research Institute, Chennai, Tamil Nadu, India.ORCID http://orcid.org/0000-0002-8350-5674
Wajith Z HussainDepartment of Endocrine and Breast Surgery, Madras Medical College and Research Institute, Chennai, Tamil Nadu, India.
Shikhil PuzhakkalDepartment of Endocrine and Breast Surgery, Madras Medical College and Research Institute, Chennai, Tamil Nadu, India.
Madras Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenocortical carcinomas (ACCs) are rare malignancies with an incidence of one to two per million per year. Aldosterone-producing ACCs (APACs) are extremely rare with an incidence less than 1%. We describe a rare case of APAC, presenting with episodic lower-limb weakness and hypertension. Our patient was found to have serum aldosterone levels of 20.8 ng/dL (2.5-15.2) with persistent hypokalaemia and a 9.7×8.3×7.7 cm right adrenal mass, which was suspicious of malignancy on evaluation. He underwent a complete surgical resection which confirmed the diagnosis of ACC and normalised his aldosterone and potassium levels. He was then subjected to postoperative chemotherapy. Postoperative adjuvant chemotherapy with mitotane has a role in preventing recurrence.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical CarcinomaHypertensionHypokalemic Periodic ParalysisAdrenal CortexAdrenalectomyAdultAldosteroneChemotherapy, AdjuvantDiagnosis, DifferentialHumansMalePotassiumTomography, X-Ray ComputedTreatment OutcomeAldosteronePotassiumadrenal disordersendocrine cancerhypertensionsurgical oncologyurological surgery

Identifiers

PMID32912887
PMCPMC7482498
OpenAlexW3086729228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.