Evidence map›Paper›PMID 32912870›Full record

ArticleAJNR. American journal of neuroradiology2020

Diffuse Leptomeningeal Glioneuronal Tumor of Childhood.

D A Lakhani, K Mankad, S Chhabda, P Feizi, R Patel, A Sarma, S Pruthi

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Amelanotic melanoma of the central nervous system with systemic spread - imaging pitfalls and clues in a rare paediatric case with congenital melanocytic naevi.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
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  13. Imaging of pediatric glioneuronal and neuronal tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Diffuse leptomeningeal glioneuronal tumor in an 8-year-old girl: case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

D A LakhaniFrom the Department of Radiology (D.A.L., P.F.), School of Medicine, West Virginia University, Morgantown, West Virginia.ORCID 0000-0001-7577-1887
K MankadDepartment of Neuroradiology (K.M., S.C.), Great Ormond Street Hospital (GOSH), London, UK.ORCID 0000-0001-5979-9337
S ChhabdaDepartment of Neuroradiology (K.M., S.C.), Great Ormond Street Hospital (GOSH), London, UK.ORCID 0000-0003-1191-1187
P FeiziFrom the Department of Radiology (D.A.L., P.F.), School of Medicine, West Virginia University, Morgantown, West Virginia.ORCID 0000-0002-5965-8937
R PatelDepartment of Diagnostic and Interventional Imaging, Section of Neuroradiology (R.P.), The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas.ORCID 0000-0002-0891-1541
A SarmaDepartment of Radiology and Radiological Sciences (A.S., S.P.), Monroe Carell Jr. Children's Hospital, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0003-4496-3637
S PruthiDepartment of Radiology and Radiological Sciences (A.S., S.P.), Monroe Carell Jr. Children's Hospital, Vanderbilt University Medical Center, Nashville, Tennessee. sumit.pruthi@vumc.org.ORCID 0000-0002-4035-0852
Great Ormond Street Hospital · GBMonroe Carell Jr. Children's Hospital · USWest Virginia University · USThe University of Texas Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse leptomeningeal glioneuronal tumor is a newly defined entity under the neuronal and mixed neuronal-glial tumors category in the 2016 World Health Organization classification of brain tumors. In this series, we report clinical, radiologic, and histologic findings in 7 cases of diffuse leptomeningeal glioneuronal tumor. Our cases and literature review indicate that the most characteristic imaging finding is diffuse intracranial and intraspinal nodular leptomeningeal thickening and enhancement. This is often associated with small cyst-like, nonenhancing lesions. It should be noted that tumors sometimes bear nontypical features, for example, presenting as a solitary spinal cord mass without leptomeningeal involvement or with a dominant intracranial mass. In children with characteristic imaging findings and without clinical features of infection, the radiologist has an opportunity to promptly raise the possibility of diffuse leptomeningeal glioneuronal tumor, and thereby, affect streamlined diagnostic evaluation.

Indexed as

AdolescentBrain NeoplasmsChildHumansMagnetic Resonance ImagingMaleMeningeal NeoplasmsSpinal Cord Neoplasms

Identifiers

PMID32912870
PMCPMC7658820
OpenAlexW3085757299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.