SynthesisWorld journal of emergency surgery : WJES2020
Extracorporeal membrane oxygenation in trauma patients: a systematic review.
Synthesis in World journal of emergency surgery : WJES, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Guidelines for Enhanced Recovery After Trauma and Intensive Care (ERATIC): Enhanced Recovery After Surgery (ERAS) and International Association for Trauma Surgery and Intensive Care (IATSIC) Society Recommendations: Paper 2: Postoperative and Intensive Care Recommendations.World journal of surgery · 2025Guideline
- ECMO in adult patients with severe trauma: a systematic review and meta-analysis.European journal of medical research · 2023Pooled it
- Extracorporeal membrane oxygenation improves survival for trauma patients: fact, fiction, or the future?Trauma surgery & acute care open · 2026Article
- Pathogenesis of MRSA-influenza co-infection: implications for ECMO therapeutic strategies - a mini-review.Frontiers in immunology · 2026Review
- Cardiopulmonary bypass as adjunct for repair of iliac vein confluence injury.Journal of vascular surgery cases and innovative techniques · 2025Article
- Challenges of ECMO use for severe trauma: a narrative review.Hereditas · 2025Review
- Thoracic trauma WSES-AAST guidelines.World journal of emergency surgery : WJES · 2025Review
- Prehospital extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest in goat with severe primary blast lung Injury-a pilot study.Journal of cardiothoracic surgery · 2025Article
- Successful laparotomy for intra-abdominal hypertension following veno-venous extracorporeal membrane oxygenation after severe thoracoabdominal trauma: a case report.Journal of trauma and injury · 2025Article
- Extracorporeal membrane oxygenation in trauma: a single-center retrospective observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Observational
- Rising Above the Limits of Critical Care ECMO: A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Traumatic Bronchus Avulsion Managed With Extracorporeal Membrane Oxygenation, Pneumonectomy, and Rib Fixation.Case reports in surgery · 2025Article
- Surgical stabilization of rib fractures in conjunction with veno-venous ECMO for traumatic chest wall injury: a multi-institutional case series from the Chest Wall Injury Society (CWIS).Trauma surgery & acute care open · 2025Article
- Extracorporeal Membrane Oxygenation-Assisted Thoracic Surgery: A Series of 10 Cases.Surgical case reports · 2025Article
- Article
- Use of extracorporeal membrane oxygenation during a decompressive hemicraniectomy for severe traumatic brain injury: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Neurosurgical Procedures in Patients Requiring Extracorporeal Membrane Oxygenation.Critical care explorations · 2024Article
- Management of penetrating cardiac injury and tricuspid regurgitation with extracorporeal-membrane oxygenation (ECMO): a case report.Journal of cardiothoracic surgery · 2024Article
- Approach to traumatic cardiac arrest in the emergency department: a narrative literature review for emergency providers.World journal of emergency medicine · 2024Review
- Early veno-venous extracorporeal membrane oxygenation is an effective strategy for traumatically injured patients presenting with refractory respiratory failure.The journal of trauma and acute care surgery · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtracorporeal membrane oxygenation (ECMO) has evolved considerably over the past two decades and has been gradually utilized in severe trauma. However, the indications for the use of ECMO in trauma remain uncertain and the clinical outcomes are different. We performed a systematic review to provide an overall estimate of the current performance of ECMO in the treatment of trauma patients. MATERIALS AND
methodsWe searched PubMed and MEDLINE databases up to the end of December 2019 for studies on ECMO in trauma. The PRISMA statement was followed. Data on demographics of the patient, mechanism of injury, injury severity scores (ISS), details of ECMO strategies, and clinical outcome were extracted.
resultsA total of 58 articles (19 retrospective reports and 39 case reports) were deemed eligible and included. In total, 548 patients received ECMO treatment for severe trauma (adult 517; children 31; mean age of adults 34.9 ± 12.3 years). Blunt trauma (85.4%) was the primary injury mechanism, and 128 patients had traumatic brain injury (TBI). The mean ISS was 38.1 ± 15.0. A total of 71.3% of patients were initially treated with VV ECMO, and 24.5% were placed on VA ECMO. The median time on ECMO was 9.6 days, and the median time to ECMO was 5.7 days. A total of 60% of patients received initially heparin anticoagulation. Bleeding (22.9%) and thrombosis (19%) were the most common complications. Ischemia of the lower extremities occurred in 9 patients. The overall hospital mortality was 30.3%.
conclusionsECMO has been gradually utilized in a lifesaving capacity in severe trauma patients, and the feasibility and advantages of this technique are becoming widely accepted. The safety and effectiveness of ECMO in trauma require further study. Several problems with ECMO in trauma, including the role of VA-ECMO, the time to institute ECMO, and the anticoagulation strategy remain controversial and must be solved in future studies.
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