ArticleBMC oral health2020
The profile of hematinic deficiencies in patients with oral lichen planus: a case-control study.
Article in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- How Nutrient Deficiencies Impact the Oral Mucosa and How to Manage Them: A Narrative Review.Nutrients · 2026Review
- Relationship Between Anemia and Oral Lichen Planus: New Therapeutic Perspectives Based on Anemia Management-A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Clinical and Pathophysiological Significance of Trace Elements in Oral Potentially Malignant Disorders and Oral Cancer: A 20-Year Narrative Review for Evidence-Based Public Health Intervention.International journal of dentistry · 2026Review
- Salivary iron and Candida colonization in oral lichen planus patients undergoing topical steroid therapy.BMC oral health · 2025Article
- Proteomic Profiling of Serum-Derived Exosomes in Oral Lichen Planus: FN1-C3-ECM Crosstalk as a Potential Novel Therapeutic Target.Journal of inflammation research · 2025Article
- Role of Vitamin D in Oral Lichen Planus: A Case Control Study.Nutrients · 2024Article
- Significantly higher serum levels and positive rates of tumor biomarkers in patients with oral lichen planus.Journal of dental sciences · 2023Article
- Vitamin B12 deficiency may play an etiological role in atrophic glossitis and its grading: A clinical case-control study.BMC oral health · 2022Article
- Diagnostic value of oral "beefy red" patch combined with fingertip blood mean corpuscular volume in vitamin B12 deficiency.BMC oral health · 2022Article
- Rekindling the role of plasma Vitamin BJournal of oral and maxillofacial pathology : JOMFPArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOral lichen planus (OLP) is a relatively common mucocutaneous disorder, and its causative factors and pathogenesis are not fully understood. Existing studies on the association between hematinic deficiencies and OLP are limited and inconsistent. The aim of this study was to assess the hematinic deficiencies in a cohort of OLP patients and evaluate the correlation between hematinic deficiencies and OLP.
methodsA total of 236 OLP patients and 226 age-and-gender-matched healthy controls were enrolled in this study. The levels of hemoglobin (Hb), serum folate, vitamin B12 and ferritin were measured and compared between OLP patients and healthy controls. An REU (reticular/hyperkeratotic, erosive/erythematous, ulcerative) scoring system was adopted and compared between the OLP patients with and without hematinic deficiencies. The correlation between hematinic deficiencies and OLP was analyzed.
resultsThe frequencies of serum ferritin and vitamin B12 deficiency in OLP patients were both significantly higher than those of the healthy controls. According to gender and age, the profiles of hematinic deficiencies in OLP patients were significantly different. As for the REU score, no significant difference existed between OLP patients with and without hematinic deficiencies. Both serum ferritin deficiency and serum vitamin B12 deficiency were significantly correlated with OLP.
conclusionsThe present study suggested a significant association between hematinic deficiencies and OLP. Iron, folate, and vitamin B12 levels in OLP patients should be monitored routinely. Further studies are warranted to explore the interactions between OLP and hematinic deficiencies.
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