Evidence map›Paper›PMID 32912207›Full record

ArticleBMC complementary medicine and therapies2020

Schisandra chinensis bee pollen's chemical profiles and protective effect against H

Peiying Shi, Qianqian Geng, Lifu Chen, Tianyu Du, Yan Lin, Rongcai Lai, Fei Meng, Zhenhong Wu, Xiaoqing Miao, Hong Yao

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  4. Drug design, development and therapy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Peiying ShiDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Qianqian GengDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Lifu ChenDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Tianyu DuDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Yan LinDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Rongcai LaiDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Fei MengDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Zhenhong WuDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Xiaoqing MiaoDepartment of Traditional Chinese Medicine Resource and Bee Products, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, China.
Hong YaoDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, 1 Xue Yuan Road, University Town, Fuzhou, 350122, People's Republic of China. hongyao@mail.fjmu.edu.cn.ORCID http://orcid.org/0000-0003-3826-934X
Fujian Agriculture and Forestry University · CNFujian Medical University · CN

Funding

Earmarked Fund for Modern Agro-industry Technology Research System CARS-45-KXJ20Joint Funds for the Innovation of Science and Technology, Fujian province 2017Y9123National Nature Science Foundation of China 81973558Natural Science Foundation of Fujian Province 2018J01596Program for New Century Excellent Talents in Fujian Province University (2018) NoneTraining Program for Excellent Scientific Research Talents of Young Teachers in Fujian Province University (2017) None
6 · The paper itself

Abstract

backgroundSchisandra chinensis (Turcz.) Baill bee pollen extract (SCBPE) is often used as a functional food in China due to its good antioxidant property. However, its chemical compositions and effects on H9c2 cardiomyocytes against H

methodsThe main components of SCBPE were analyzed via ultraperformance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry (UPLC-QTOF MS/MS). The three main nucleosides in SCBPE were quantitatively analyzed via ultraperformance liquid chromatography-diode array detection. Furthermore, the potential mechanism by which SCBPE exerts protective effects against H

resultsTwo carbohydrates, three nucleosides, and nine quinic acid nitrogen-containing derivatives in SCBPE were identified or tentatively characterized via UPLC-QTOF MS/MS. The nine quinic acid nitrogen-containing derivatives were first reported in bee pollen. The contents of uridine, guanosine, and adenosine were 2.4945 ± 0.0185, 0.1896 ± 0.0049, and 1.8418 ± 0.0157 μg/mg, respectively. Results of in vitro experiments showed that cell survival rate, myocardial SOD activity, and GSH level significantly increased and myocardial MDA level significantly decreased in SCBPE groups compared with those in H

conclusionsThis study is the first to report that SCBPE could protect against oxidative stress injury and apoptosis in H

Indexed as

AnimalsApoptosisBeesCell LineChinaDown-RegulationHydrogen PeroxideMolecular StructureMyocardial IschemiaMyocytes, CardiacOxidative StressPollenRatsSchisandraUp-RegulationHydrogen PeroxideH2O2H9c2 cardiomyocytesNucleosidesProtective effectQuinic acid nitrogen-containing derivativesSchisandra chinensis bee pollen extract

Identifiers

PMID32912207
PMCPMC7487998
OpenAlexW3084802934

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.