Evidence map›Paper›PMID 32912173›Full record

ArticleBMC psychiatry2020

Prevalence and factors associated with severe depressive symptoms in older west African people living with HIV.

Charlotte Bernard, Hélène Font, Zélica Diallo, Richard Ahonon, Judicaël Malick Tine, Franklin N'guessan Abouo, Aristophane Tanon, Eugène Messou, Moussa Seydi, François Dabis and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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  18. Lived experience of people living with HIV in Blantyre, Malawi: an exploratory qualitative study.Malawi medical journal : the journal of Medical Association of Malawi · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Charlotte BernardBordeaux Population Health Research Center, Univ. Bordeaux, Inserm, UMR 1219, F-33000, Bordeaux, France. charlotte.bernard@u-bordeaux.fr.
Hélène FontBordeaux Population Health Research Center, Univ. Bordeaux, Inserm, UMR 1219, F-33000, Bordeaux, France.
Zélica DialloService de maladies infectieuses et tropicales, CHU Treichville, Abidjan, Côte d'Ivoire.
Richard AhononCentre de prise en charge de recherche et de formation (CePReF), Yopougon Attié Hospital, Abidjan, Côte d'Ivoire.
Judicaël Malick TineService de maladies infectieuses et tropicales, CRCF, CHNU de Fann, Dakar, Senegal.
Franklin N'guessan AbouoService de maladies infectieuses et tropicales, CHU Treichville, Abidjan, Côte d'Ivoire.
Aristophane TanonService de maladies infectieuses et tropicales, CHU Treichville, Abidjan, Côte d'Ivoire.
Eugène MessouCentre de prise en charge de recherche et de formation (CePReF), Yopougon Attié Hospital, Abidjan, Côte d'Ivoire.
Moussa SeydiService de maladies infectieuses et tropicales, CRCF, CHNU de Fann, Dakar, Senegal.
François DabisBordeaux Population Health Research Center, Univ. Bordeaux, Inserm, UMR 1219, F-33000, Bordeaux, France.
Nathalie de RekeneireBordeaux Population Health Research Center, Univ. Bordeaux, Inserm, UMR 1219, F-33000, Bordeaux, France.
IeDEA West Africa Cohort Collaboration
Université de Bordeaux · FRCentre Hospitalier National Universitaire de Fann · SNUniversity Hospital Medical Center at Treichville · CICentre Hospitalier Universitaire de Yopougon · CI

Funding

WADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9M
NIAID NIH HHS U01 AI069919
6 · The paper itself

Abstract

backgroundDepression is one of the most common psychiatric disorders in people living with HIV (PLHIV). Depression has a negative impact on both mental and physical health and is mainly associated with suboptimal HIV treatment outcomes. To encourage successful aging and the achievement of the 3 × 90 objectives in older PLHIV, the psychological domain must not be neglected. In this context and as data are scarce in West Africa, this study aimed to evaluate the prevalence and the factors associated with severe depressive symptoms in older PLHIV living in this region of the world.

methodsData from PLHIV aged ≥50 years and on ART since ≥6 months were collected in three clinics (two in Côte d'Ivoire, one in Senegal) participating in the West Africa International epidemiological Databases to Evaluate AIDS (IeDEA) collaboration. The severity of depressive symptoms was measured using the Center for Epidemiological Studies Depression scale (CES-D), and associated factors were identified using logistic regressions.

resultsThe median age of the 334 PLHIV included in the study was 56.7 (53.5-61.1), 57.8% were female, and 87.1% had an undetectable viral load. The prevalence of severe depressive symptoms was 17.9% [95% Confidence Interval (95% CI): 13.8-22.0]. PLHIV with severe depressive symptoms were more likely to be unemployed (adjusted Odd Ratio (aOR) = 2.8; 95% CI: 1.4-5.7), and to be current or former tobacco smokers (aOR = 2.6; 95% CI: 1.3-5.4) but were less likely to be overweight or obese (aOR = 0.4; 95% CI: 0.2-0.8).

conclusionsThe prevalence of severe depressive symptoms is high among older PLHIV living in West Africa. Unemployed PLHIV and tobacco smokers should be seen as vulnerable and in need of additional support. Further studies are needed to describe in more details the reality of the aging experience for PLHIV living in SSA. The integration of screening and management of depression in the standard of care of PLHIV is crucial.

Indexed as

DepressionHIV InfectionsAgedCote d'IvoireCross-Sectional StudiesFemaleHumansMaleMass ScreeningPrevalenceAgingDepressionHIVSub-Saharan Africa

Identifiers

PMID32912173
PMCPMC7481548
OpenAlexW3083913412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.