Evidence map›Paper›PMID 32912055›Full record

ArticlePalliative medicine2021

Validation of the Distress Thermometer in patients with advanced cancer receiving specialist palliative care in a hospice setting.

Lisa Graham-Wisener, Martin Dempster, Aaroon Sadler, Luke McCann, Noleen K McCorry

Registry-linked trialAbstract read
In one paragraph

Article in Palliative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07554677 (Feasibility of a Co-designed PRe-radiotherapy Exercise Programme for People With Stage I-III Non-small Cell Lung cAnCEr), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07554677 narecruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility of a Co-designed PRe-radiotherapy Exercise Programme for People With Stage I-III Non-small Cell Lung cAnCEr: A Single-centre, Single Arm Pilot Study

TypeinterventionalSponsorQueen's University, BelfastRan2026 to 2026Enrolled30ConditionsLung CancerArmsExercise, radiotherapy
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. When zero isn't nothing: excess zero scores in repeated distress screening of cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Review
  4. Distress level in newly diagnosed thyroid cancer patients and predictors of clinically significant distress.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Symptom burden, psychosocial distress and palliative care needs in heart failure - A cross-sectional explorative pilot study.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisa Graham-WisenerCentre for Improving Health-Related Quality of Life, School of Psychology, Queen's University Belfast, Belfast, UK.ORCID 0000-0001-6311-4978
Martin DempsterCentre for Improving Health-Related Quality of Life, School of Psychology, Queen's University Belfast, Belfast, UK.ORCID 0000-0001-9499-3186
Aaroon SadlerMarie Curie Hospice Belfast, Belfast, UK.
Luke McCannSouth Eastern Health and Social Care Trust, Ulster Hospital, Dundonald, Downpatrick, UK.
Noleen K McCorryCentre of Excellence in Public Health, Queen's University Belfast, Belfast, UK.ORCID 0000-0002-8542-7665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOngoing assessment of psychological reaction to illness in palliative and end of life care settings is recommended, yet validated tools are not routinely used in clinical practice. The Distress Thermometer is a short screening tool developed for use in oncology, to detect individuals who would benefit from further psychological assessment. However the optimal cut-off to detect indicative psychological morbidity in patients with advanced cancer receiving specialist palliative care is unclear.

aimTo provide the first validation of the Distress Thermometer in an advanced cancer population receiving specialist palliative care in a UK hospice setting.

designReceiver Operating Characteristics analysis was used to compare the sensitivity and specificity of cut-offs indicative of psychological morbidity on the Distress Thermometer in comparison to the Hospital Anxiety and Depression Scale. SETTING/

participantsData were derived from 202 patients with advanced cancer who were approached on admission to inpatient or day hospice care, with 139 patients providing complete data on both measures.

resultsThe area under the curve was optimal using a Distress Thermometer cut-off score of ⩾6 for total distress and for anxiety, and a cut-off score of ⩾4 optimal when screening for depression.

conclusionsThe Distress Thermometer is a valid, accurate screening tool to be used in advanced cancer but with caution in relation to the lack of specificity. With little variation between the area under the curve scores, arguably a Distress Thermometer cut-off score of ⩾5 is most appropriate in screening for all types of psychological morbidity if sensitivity is to be prioritised.

Indexed as

Hospice CareHospicesNeoplasmsHumansPalliative CarePsychometricsStress, PsychologicalSurveys and QuestionnairesThermometersadvanced canceranxietydepressiondistressdistress thermometerPalliative careterminal carevalidation studies

Identifiers

PMID32912055
PMCPMC7797615

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.