ReviewJournal of clinical medicine2020
Is There a Role for Spacer Exchange in Two-Stage Exchange Arthroplasty for Periprosthetic Joint Infection?
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Can "LITE" Procedure Combined With a Short Course Antibiotic Treatment Be Effective in Treating the Chronic PJI?-A Prospective Randomized Controlled Trial.Orthopaedic surgery · 2025Trial
- Antimicrobial Regimens in Cement Spacers for Periprosthetic Joint Infections: A Critical Review.Antibiotics (Basel, Switzerland) · 2024Review
- Articulating Hip Spacers with a Constrained Acetabular Liner: Effect of Acetabular Bone Loss and Cementation Quality.Antibiotics (Basel, Switzerland) · 2023Article
- Clinical impact of microbiological results in two-stage revision arthroplasty with spacer exchange.Archives of orthopaedic and trauma surgery · 2023Article
- Repeat two-stage exchange arthroplasty for recurrent periprosthetic hip or knee infection: what are the chances for success?Archives of orthopaedic and trauma surgery · 2023Article
- Spacer exchange in persistent periprosthetic joint infection: microbiological evaluation and survivorship analysis.Archives of orthopaedic and trauma surgery · 2023Article
- Influence of the Type of Bone Cement Used in Two-Stage Exchange Arthroplasty for Chronic Periarticular Joint Infection on the Spacer Replacement and Reinfection Rate.Journal of clinical medicine · 2023Article
- Review
- Risk of reinfection after two- or multiple-stage knee revision surgery using superficial vancomycin coating and conventional spacers.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021Article
- Prosthetic Joint Infection: Updates on Prevention, Diagnosis and Therapy.Journal of clinical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periprosthetic joint infection (PJI) continues to be one of the most serious complications after hip and knee arthroplasty. The choice of surgical treatment depends on a multitude of factors like chronicity of infection, host factors, and institutional or surgeon experience. Two-stage exchange remains one of the most commonly used technique for chronic PJI in the United States of America. The intended two-stage revision may involve an additional interim procedure where the initial antibiotic cement spacer is removed and a new spacer is inserted. Mostly, the rationale behind spacer exchange is an additional load of local antibiotics before proceeding to reimplantation. There is no conclusive evidence whether a spacer exchange confers additional benefits, yet it delays reimplantation and exposes already fragile patients to the risks and morbidity of an additional surgery.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.