Evidence map›Paper›PMID 32911819›Full record

ReviewPharmaceuticals (Basel, Switzerland)2020

Tumor Immunotherapy Using A

Jinfeng Zhang, Wenzhong Yan, Wenwen Duan, Kurt Wüthrich, Jianjun Cheng

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04969315 (Phase I/II First-in-Human Study of TT-10), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04969315 phase1 / phase2recruitingnot on this mapstarted 2023, after this paper: background citation

Phase I/II First-in-Human Study of TT-10 (PORT-6), an Adenosine 2A Receptor Antagonist, and PORT-7, an Adenosine 2B Receptor Antagonist, as Single Agents and in Combination in Participants With Advanced Selected Solid Tumors

TypeinterventionalSponsorPortage BiotechRan2023 to 2027Enrolled90ConditionsRenal Cell Cancer, Castrate Resistant Prostate Cancer, Non Small Cell Lung Cancer, Head and Neck Squamous Cell CarcinomaArmsTT-10, TT-4
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Neoantigen mRNA vaccines and AHuman vaccines & immunotherapeutics · 2025
    Review
  5. Review
  6. Insights from Clinical Trials on AACS pharmacology & translational science · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. AInternational review of neurobiology · 2023
    Article
  11. Special Issue "GPCRs: Ligands and beyond 2022".Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jinfeng ZhangiHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Wenzhong YaniHuman Institute, ShanghaiTech University, Shanghai 201210, China.ORCID 0000-0003-0420-9138
Wenwen DuaniHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Kurt WüthrichiHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Jianjun ChengiHuman Institute, ShanghaiTech University, Shanghai 201210, China.ORCID 0000-0001-6065-2682
ShanghaiTech University · CNScripps Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The A

Indexed as

cancer therapydrug binding modesGPCRimmuno-oncologyParkinson’s disease

Identifiers

PMID32911819
PMCPMC7558881
OpenAlexW3084411570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.