Evidence map›Paper›PMID 32911795›Full record

ReviewInternational journal of molecular sciences2020

An Update on Vitamin D Metabolism.

Federica Saponaro, Alessandro Saba, Riccardo Zucchi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 5 pooled it
21.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 5 syntheses or guidelines pooled it, 303 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. The effects of low-fat dairy products fortified with 1500 IU vitamin DJournal of health, population, and nutrition · 2023
    Trial
  8. Review
  9. Article
  10. Article
  11. In ovo injection of vitamin DPoultry science · 2026
    Article
  12. Article
  13. Review
  14. Prenatal Aflatoxin BToxins · 2026
    Review
  15. Article
  16. Review
  17. Vitamin DFrontiers in immunology · 2026
    Review
  18. Article
  19. Article
  20. Review

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Federica SaponaroDepartment of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-0277-1648
Alessandro SabaDepartment of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-0611-5549
Riccardo ZucchiDepartment of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D is a steroid hormone classically involved in the calcium metabolism and bone homeostasis. Recently, new and interesting aspects of vitamin D metabolism has been elucidated, namely the special role of the skin, the metabolic control of liver hydroxylase CYP2R1, the specificity of 1α-hydroxylase in different tissues and cell types and the genomic, non-genomic and epigenomic effects of vitamin D receptor, which will be addressed in the present review. Moreover, in the last decades, several extraskeletal effects which can be attributed to vitamin D have been shown. These beneficial effects will be here summarized, focusing on the immune system and cardiovascular system.

Indexed as

25-Hydroxyvitamin D3 1-alpha-HydroxylaseAnimalsBone and BonesCalcitriolCytochrome P-450 Enzyme SystemCytochrome P450 Family 2HomeostasisHumansLipid MetabolismMixed Function OxygenasesReceptors, CalcitriolSkinVitamin DVitamin D3 24-Hydroxylase25-Hydroxyvitamin D3 1-alpha-HydroxylaseCalcitriolCytochrome P-450 Enzyme SystemCytochrome P450 Family 2Mixed Function OxygenasesReceptors, CalcitriolVDR protein, humanVitamin DVitamin D3 24-Hydroxylase1,25(OH)2D25OH-vitamin DVDRvitamin Dvitamin D receptor

Identifiers

PMID32911795
PMCPMC7554947
OpenAlexW3084059564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.