ArticleLife (Basel, Switzerland)2020
Muscle Hypertrophy and Architectural Changes in Response to Eight-Week Neuromuscular Electrical Stimulation Training in Healthy Older People.
Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07668258 (A Single-Center, Randomized, Double-Blind, Sham-Controlled Clinical Trial to Evaluate the Efficacy of Neuromuscular Electrical Stimulation Therapy for Improving Lower-Limb Strength and Physical Performance in Patients With Sarcopenia), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single-Center, Randomized, Double-Blind, Sham-Controlled Clinical Trial to Evaluate the Efficacy of Neuromuscular Electrical Stimulation Therapy for Improving Lower-Limb Strength and Physical Performance in Patients With Sarcopenia
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- The additive effect of neuromuscular electrical stimulation and resistance training on muscle mass and strength.European journal of applied physiology · 2025Pooled it
- Combined Use of Transcutaneous Electrical Nerve Stimulation and Short Foot Exercise Improves Navicular Height, Muscle Size, Function Mobility, and Risk of Falls in Healthy Older Adults.International journal of environmental research and public health · 2022Trial
- Seven months of aerobic intradialytic exercise training can prevent muscle loss in haemodialysis patients: an ultrasonography study.International urology and nephrology · 2022Trial
- Systemic Oxy-Inflammatory, Hormonal, and Mood Responses to a Ski Mountaineering Competition: Preliminary Evidence from Military Athletes.Sports (Basel, Switzerland) · 2026Article
- Nanotechnology-mediated strategies for skeletal muscle repair and regeneration: targeted intervention, functional remodeling, and translational challenges.Journal of nanobiotechnology · 2026Review
- Acute changes in ankle dorsiflexor strength and fNIRS-Derived cortical activation following a single session of neuromuscular electrical stimulation in healthy older adults.Frontiers in aging · 2026Article
- The Effect of a 10-Week Electromyostimulation Intervention with the StimaWELL 120MTRS System on Multifidus Morphology and Function in Chronic Low Back Pain Patients: A Randomized Controlled Trial.Journal of functional morphology and kinesiology · 2025Article
- Skeletal muscle dysfunction with advancing age.Clinical science (London, England : 1979) · 2024Review
- Functional Repetitive Neuromuscular Magnetic Stimulation (frNMS) Targeting the Tibialis Anterior Muscle in Children with Upper Motor Neuron Syndrome: A Feasibility Study.Children (Basel, Switzerland) · 2023Article
- Ultrasound Measurements of Rectus Femoris and Locomotor Outcomes in Patients with Spinal Cord Injury.Life (Basel, Switzerland) · 2022Article
- Long-Term Effect of Exercise on Irisin Blood Levels-Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2021Review
- Age-related alterations in muscle architecture are a signature of sarcopenia: the ultrasound sarcopenia index.Journal of cachexia, sarcopenia and muscle · 2021Article
- Editorial: Sarcopenia: 2020.The journal of nutrition, health & aging · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Loss of muscle mass of the lower limbs and of the spine extensors markedly impairs locomotor ability and spine stability in old age. In this study, we investigated whether 8 w of neuromuscular electrical stimulation (NMES) improves size and architecture of the lumbar multifidus (LM) and vastus lateralis (VL) along with locomotor ability in healthy older individuals. Eight volunteers (aged 65 ≥ years) performed NMES 3 times/week. Eight sex- and age-matched individuals served as controls. Functional tests (Timed Up and Go test (TUG) and Five Times Sit-to-Stand Test (FTSST)), VL muscle architecture (muscle thickness (MT), pennation angle (PA), and fiber length (FL)), along with VL cross-sectional area (CSA) and both sides of LM were measured before and after by ultrasound. By the end of the training period, MT and CSA of VL increased by 8.6% and 11.4%, respectively. No significant increases were observed in FL and PA. LM CSA increased by 5.6% (left) and 7.1% (right). Interestingly, all VL architectural parameters significantly decreased in the control group. The combined NMES had a large significant effect on TUG (r = 0.50,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.