ArticleBiomolecules2020
Targeting the Id1-Kif11 Axis in Triple-Negative Breast Cancer Using Combination Therapy.
Open access · goldAbstract read
In one paragraph
Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 11 citations in OpenAlex.
- Cancer Stem Cell Quiescence: Molecular and Microenvironmental Evidence for an Actively Regulated Adaptive Survival Strategy.Cancer medicine · 2026Review
- The Role of PGC-1α in Neurodegenerative Diseases: Molecular Mechanisms, Translational Challenges, and Therapeutic Potential.Molecular neurobiology · 2026Review
- FOXM1 Signaling Network Transcriptionally Upregulates Expression of Proteins Involved in Mitotic Progression to Induce High Proliferation and Chromosomal Instability in Androgen Receptor-Low Triple-Negative Breast Cancer.International journal of molecular sciences · 2026Article
- Inhibitor of DNA binding 1 in lung cancer and the tumor microenvironment: a testable hypothesis for malignant pleural effusion formation.Frontiers in immunology · 2026Review
- Article
- Kinesin Spindle Protein (KIF11) in Mitosis and Cancer.International journal of molecular sciences · 2025Review
- Exploring ID4 as a driver of aggression and a therapeutic target in triple-negative breast cancer.NPJ breast cancer · 2025Article
- The Critical Role of Inhibitor of Differentiation 4 in Breast Cancer: From Mammary Gland Development to Tumor Progression.Cancer medicine · 2025Review
- Identification and validation of the important role of KIF11 in the development and progression of endometrial cancer.Journal of translational medicine · 2025Article
- Proteomic Analysis Revealed the Potential Role of MAGE-D2 in the Therapeutic Targeting of Triple-Negative Breast Cancer.Molecular & cellular proteomics : MCP · 2024Article
- Kinesin family member 11 promotes progression of hepatocellular carcinoma via the OCT4 pathway.Functional & integrative genomics · 2023Article
- Cyclovirobuxine D inhibits growth and progression of non‑small cell lung cancer cells by suppressing the KIF11‑CDC25C‑CDK1‑CyclinB1 GInternational journal of oncology · 2023Article
- Phenotypic heterogeneity drives differential disease outcome in a mouse model of triple negative breast cancer.Frontiers in oncology · 2023Article
- Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel.International journal of molecular sciences · 2021Article
- Prospects of Immunotherapy for Triple-Negative Breast Cancer.Frontiers in oncology · 2021Review
- KIF11 Serves as an Independent Prognostic Factor and Therapeutic Target for Patients With Lung Adenocarcinoma.Frontiers in oncology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 3 countries.
Archana P ThankamonyCancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala 695014, India.
Reshma MuraliCancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala 695014, India.
Nitheesh KarthikeyanCancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala 695014, India.
Binitha Anu VargheseCancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala 695014, India.
Wee S TeoThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Andrea McFarlandThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Daniel L RodenThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Holly HollidayThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.ORCID 0000-0002-3022-0114
Christina Valbirk KonradThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.ORCID 0000-0002-7172-8424
Aurelie CazetThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Eoin DodsonThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Jessica YangThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Laura A BakerThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Jason T GeorgeCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.ORCID 0000-0002-8248-2888
Herbert LevineCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA.ORCID 0000-0002-8819-9055
Mohit Kumar JollyCentre for BioSystems Science and Engineering, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0002-6631-2109
Alexander SwarbrickThe Kinghorn Cancer Centre and Cancer Research Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Radhika NairCancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala 695014, India.ORCID 0000-0002-6585-3384
Garvan Institute of Medical Research · AURajiv Gandhi Centre for Biotechnology · INBaylor College of Medicine · USIndian Institute of Science Bangalore · INManipal Academy of Higher Education · INNortheastern University · US
Funding
Early Career Research Award from SERB ECR/2015/000031Ramanujan Fellowship, SERB, Government of India SB/S2/RJN/182/2014
Abstract
The basic helix-loop-helix (bHLH) transcription factors inhibitor of differentiation 1 (
Indexed as
AnimalsAntineoplastic Combined Chemotherapy ProtocolsAurora Kinase ABenzamidesCell CycleCell Line, TumorCell Self RenewalFemaleGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansInhibitor of Differentiation Protein 1KinesinsMiceNeoplastic Stem CellsPaclitaxelAurka protein, mouseAurora Kinase ABenzamidesID1 protein, humanIdb1 protein, mouseInhibitor of Differentiation Protein 1ispinesibKIF11 protein, humanKif11 protein, mouseKinesinsPaclitaxelQuinazolinescancer stem cellschemoresistancecombination therapyId1Kif11self-renewal
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.