Evidence map›Paper›PMID 32911630›Full record

ArticleJournal of clinical medicine2020

Time Trends of Crohn's Disease in Catalonia from 2011 to 2017. Increasing Use of Biologics Correlates with a Reduced Need for Surgery.

Eduard Brunet, Emili Vela, Luigi Melcarne, Montserrat Clèries, Caridad Pontes, Laura Patricia Llovet, Pilar García-Iglesias, Marta Gallach, Albert Villòria, Mercedes Vergara and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Long-term perineal wound healing and re-operation rates after proctectomy in patients with inflammatory bowel disease-A retrospective multicentre study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Eduard BrunetServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.ORCID 0000-0001-8661-0608
Emili VelaUnitat d'Informació i Coneixement, Servei Català de la Salut, Generalitat de Catalunya, 08002 Barcelona, Spain.
Luigi MelcarneServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.ORCID 0000-0002-9718-9692
Montserrat ClèriesUnitat d'Informació i Coneixement, Servei Català de la Salut, Generalitat de Catalunya, 08002 Barcelona, Spain.
Caridad PontesÀrea del Medicament, Servei Català de la Salut, 08002 Barcelona, Spain.
Laura Patricia LlovetServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.
Pilar García-IglesiasServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.
Marta GallachServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.
Albert VillòriaServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.
Mercedes VergaraServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.
Xavier CalvetServei Aparell Digestiu, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.ORCID 0000-0002-6278-9663
Universitat Autònoma de Barcelona · ESGeneralitat de Catalunya · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsData from clinical trials suggest that biological drugs may improve the outcomes in Crohn's disease (CD) by reducing the need for surgery or hospitalization. The aim of this study is to evaluate the time-trends of the use of biological drugs and other treatments for CD, and its relationship with outcomes in Catalonia. MATERIALS AND

methodsAll patients with CD included in the Catalan Health Surveillance System (containing data on a population of more than 7.5 million) from 2011 to 2017 were identified. The exposures to different treatments for inflammatory bowel disease were retrieved from electronic invoicing records.

resultsBetween 2011 and 2017, the use of salicylates, corticosteroids and immunosuppressive treatment fell from 28.8% to 17.1%, 15.8% to 13.7%, and 32.9% to 29.6%, respectively (

conclusionsBiological drug use rose from 15.0% to 18.7% between 2011 and 2017. During this period, we observed an improvement in the outcomes of CD patients.

Indexed as

Crohn’s diseaseepidemiologyinflammatory bowel disease

Identifiers

PMID32911630
PMCPMC7563515
OpenAlexW3083962130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.