ArticlePloS one2020
Active TB case finding in a high burden setting; comparison of community and facility-based strategies in Lusaka, Zambia.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Active Case Finding for Tuberculosis in Migrants: a Systematic Review.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2024Pooled it
- Facilitators and barriers to tuberculosis active case findings in low- and middle-income countries: a systematic review of qualitative research.BMC infectious diseases · 2023Pooled it
- Clinical and radiographic characteristics of presumptive tuberculosis patients previously treated for tuberculosis in Zambia.PloS one · 2022Trial
- Trial
- Community-based mobile tuberculosis clinics in rural Madagascar: impact and cost-effectiveness analysis.BMJ global health · 2025Article
- Finding the missing men with tuberculosis: a participatory approach to identify priority interventions in Uganda.Health policy and planning · 2025Article
- Barriers and facilitators of implementing public-private mix approaches for active tuberculosis case finding and health insurance access in at-risk populations in Ghana: a qualitative study.Frontiers in health services · 2025Article
- Evaluating InferVision's Computer-Aided Detection (CAD) algorithm for Tuberculosis (TB) screening, Lusaka, Zambia.PLOS global public health · 2025Article
- Confirming non-endemicity of podoconiosis in Guatemala and in Idukki District in Kerala (India): a comparison of two approaches potentially suitable for other neglected tropical diseases.BMC global and public health · 2024Article
- Individual, community and health systems factors influencing time to notification of tuberculosis: situating software and hardware bottlenecks in local health systems.BMC health services research · 2024Article
- Demographic and socioeconomic disparity in knowledge, attitude, and practice towards tuberculosis in Northwest, China: evidence from multilevel model study.BMC health services research · 2024Article
- Article
- Improving TB detection among children in routine clinical care through intensified case finding in facility-based child health entry points and decentralized management: A before-and-after study in Nine Sub-Saharan African Countries.PLOS global public health · 2024Article
- The TB Surge intervention: an optimized approach to TB case-finding in Nigeria.Public health action · 2023Article
- Mass Tuberculosis Screening Among the Elderly: A Population-Based Study in a Well-Confined, Rural County in Eastern China.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Article
- The Performance of Computer-Aided Detection Digital Chest X-ray Reading Technologies for Triage of Active Tuberculosis Among Persons With a History of Previous Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- A mixed methods study on men's and women's tuberculosis care journeys in Lusaka, Zambia-Implications for gender-tailored tuberculosis health promotion and case finding strategies.PLOS global public health · 2023Article
- Article
- Patient Preferences for Strategies to Improve Tuberculosis Diagnostic Services in Zambia.JAMA network open · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe conducted an implementation science study to increase TB case detection through a combination of interventions at health facility and community levels. We determined the impact of the study in terms of additional cases detected and notification rate and compared the yield of bacteriologically confirmed TB of facility based and community based case finding. METHODOLOGY: Over a period of 18 months, similar case finding activities were conducted at George health facility in Lusaka Zambia and its catchment community, an informal peri-urban settlement. Activities included awareness and demand creation activities, TB screening with digital chest x-ray or symptom screening, sputum evaluation using geneXpert MTB/RIF, TB diagnosis and linkage to treatment.
resultsA total of 18,194 individuals were screened of which 9,846 (54.1%) were screened at the facility and 8,348 (45.9%) were screened in the community. The total number of TB cases diagnosed during the intervention period were 1,026, compared to 759 in the pre-intervention period; an additional 267 TB cases were diagnosed. Of the 563 bacteriologically confirmed TB cases diagnosed under the study, 515/563 (91.5%) and 48/563 (8.5%) were identified at the facility and in the community respectively (P<0.0001). The TB notification rate increased from 246 per 100,000 population pre-intervention to 395 per 100,000 population in the last year of the intervention.
conclusionsFacility active case finding was more effective in detecting TB cases than community active case finding. Strengthening health systems to appropriately identify and evaluate patients for TB needs to be optimised in high burden settings. At a minimum, provider initiated TB symptom screening with completion of the TB screening and diagnostic cascade should be provided at the health facility in high burden settings. Community screening needs to be systematic and targeted at high risk groups and communities with access barriers.
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