Evidence map›Paper›PMID 32911059›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2021

Trends in US hospitalizations for anaphylaxis among infants and toddlers: 2006 to 2015.

Lacey B Robinson, Anna Chen Arroyo, Mohammad Kamal Faridi, Susan A Rudders, Carlos A Camargo

Open access · greenAbstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Food-induced anaphylaxis in children less than 2 years of age.Postepy dermatologii i alergologii · 2025
    Article
  3. Article
  4. Article
  5. Anaphylaxis knowledge gaps and future research priorities: A consensus report.The Journal of allergy and clinical immunology · 2022
    Article
  6. The 2020 update on anaphylaxis in paediatric population.Postepy dermatologii i alergologii · 2022
    Review
  7. Anaphylaxis: Data Gaps and Research Needs.Immunology and allergy clinics of North America · 2022
    Review
  8. Review
  9. Trends in US Emergency Department Visits for Anaphylaxis Among Infants and Toddlers: 2006-2015.The journal of allergy and clinical immunology. In practice · 2021
    Article
  10. Infant Anaphylaxis: A Diagnostic Challenge.Current allergy and asthma reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Lacey B RobinsonDivision of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: lbrobinson@mgh.harvard.edu.
Anna Chen ArroyoDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medcine, Stanford University School of Medicine, Stanford, California.
Mohammad Kamal FaridiEmergency Medicine Network, Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Susan A RuddersDivision of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Carlos A CamargoDivision of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Emergency Medicine Network, Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Massachusetts General Hospital · USBoston Children's Hospital · USHarvard University · USStanford University · US

Funding

Research Training in Pulmonary Immunology and Allergy at MGHT32HL116275 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI David C Christiani, ANDREW D LUSTER · 2013 to 2026
$8.6M
NHLBI NIH HHS T32 HL116275
6 · The paper itself

Abstract

backgroundAnaphylaxis is a potentially fatal acute allergic reaction. Its overall prevalence appears to be rising, but little is known about US hospitalization trends among infants and toddlers.

objectiveTo identify the trends and predictors of hospitalization for anaphylaxis among infants and toddlers.

methodsWe used the nationally representative National Inpatient Sample (NIS), from 2006 to 2015, to perform an analysis of trends in US hospitalizations for anaphylaxis among infants and toddlers (age, <3 years) and other children (age, 3-18 years). For internal consistency, we identified patients with anaphylaxis by the International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis code and excluded those with the International Classification of Diseases, Tenth Revision, Clinical Modification (late 2015). We calculated trends in anaphylaxis hospitalizations over time by age group and then used multivariable logistic regression to describe anaphylaxis hospitalizations among infants and toddlers.

resultsAmong infants and toddlers, there was no significant change in anaphylaxis hospitalizations during the 10-year study period (P

conclusionAnaphylaxis hospitalizations among infants and toddlers in the United States were stable from 2006 to 2015, whereas hospitalizations among older children were rising. Future research should focus on the trends in disease prevalence and health care utilization in the understudied population of infants and toddlers.

Indexed as

AdolescentAnaphylaxisChildChild, PreschoolFemaleHospitalizationHumansInfantMaleUnited States

Identifiers

PMID32911059
PMCPMC8686187
OpenAlexW3092283995

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.