Evidence map›Paper›PMID 32910695›Full record

ArticleCanadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes2021

Volumetric Markers of Body Composition May Improve Personalized Prediction of Major Arterial Bleeding After Pelvic Fracture: A Secondary Analysis of the Baltimore CT Prediction Model Cohort.

David Dreizin, Remberto Rosales, Guang Li, Hassan Syed, Rong Chen

Open access · greenAbstract read
In one paragraph

Article in Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David DreizinDepartment of Diagnostic Radiology and Nuclear Medicine, R Adams Cowley Shock Trauma Center, 12264University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-0176-0912
Remberto RosalesDepartment of Diagnostic Radiology and Nuclear Medicine, R Adams Cowley Shock Trauma Center, 12264University of Maryland School of Medicine, Baltimore, MD, USA.
Guang LiDepartment of Diagnostic Radiology and Nuclear Medicine, 12264University of Maryland School of Medicine, Baltimore, MD, USA.
Hassan SyedDepartment of Diagnostic Radiology and Nuclear Medicine, R Adams Cowley Shock Trauma Center, 12264University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0001-7641-5198
Rong ChenDepartment of Diagnostic Radiology and Nuclear Medicine, 12264University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-1298-9381
University of Maryland, Baltimore · US

Funding

Machine learning-based segmentation and risk modeling for real-time prediction of major arterial bleeding after pelvic fracturesK08EB027141 · NIBIB · UNIVERSITY OF MARYLAND BALTIMORE · PI DREIZIN, DAVID · 2019 to 2022
$745k
NIBIB NIH HHS K08 EB027141
6 · The paper itself

Abstract

methodsThis work is a retrospective secondary analysis of a single institution cohort used in the development of the Baltimore CT prediction model. The cohort includes 115 consecutive patients that underwent admission contrast-enhanced CT of the abdomen and pelvis for blunt trauma with pelvic ring disruption followed by conventional angiography. Major arterial injury requiring angioembolization served as the outcome variable. Angioembolization was required in 73/115 patients (63% of the cohort). Average age was 46.9 years (±SD 20.4). Body composition measurements were determined as 2-dimensional (2D) or 3-dimensional (3D) parameters and included mid-L3 trabecular bone attenuation, abdominal visceral fat area or volume, and percent muscle fat fraction (as a marker of sarcopenia) measured using segmentation and histogram analysis.

resultsModels incorporating 2D (Model B) or 3D markers (model C) of body composition showed improvement over the original Baltimore model (model A) in all parameters of performance, quality, and fit (area under the receiver-operating curve [AUC], Akaike information criterion, Brier score, Hosmer-Lemeshow test, and adjusted-R2). Area under the receiver-operating curve increased from 0.83 (A), to 0.86 (B), and 0.88 (C). The greatest improvement was seen with 3D parameters.

conclusionOnce automated, quantitative visualization tools providing "free" 3D body composition information can be expected to improve personalized precision diagnostics, outcome prediction, and decision support in patients with bleeding pelvic fractures.

Indexed as

Body CompositionBaltimoreCohort StudiesFemaleFractures, BoneHemorrhageHumansMaleMiddle AgedPelvic BonesPredictive Value of TestsRetrospective StudiesTomography, X-Ray Computedbody composition biomarkersCTmultivariable modelingpelvic fracturespersonalized predictionprecision diagnosticsquantitative imaging

Identifiers

PMID32910695
PMCPMC8011455
OpenAlexW3084691854

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.