Evidence map›Paper›PMID 32910543›Full record

ArticleJournal of applied clinical medical physics2020

Associating dose-volume characteristics with theoretical radiobiological metrics for rapid Gamma Knife stereotactic radiosurgery plan evaluation.

Christopher J Tien, James E Bond, Zhe Jay Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christopher J TienDepartment of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA.
James E BondDepartment of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA.
Zhe Jay ChenDepartment of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA.
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine general dose-volume characteristics in Gamma Knife (GK) plans which may be associated with higher tumor control probability (TCP) and equivalent uniform dose (EUD) using characteristic curve sets.

methodsTwo sets of dose-volume histograms (DVHs) were exported alongside an analytical purpose-generated DVH: (a) single-shot large collimator (8 or 16 mm) emulated with multiple shots of 4 mm collimator. (b) shot-within-shot (SWS) technique with isodose lines (IDLs) of 40-75%. TCP, average dose, EUD in single-fraction (EUD

resultsUsing α = 0.20 Gy

conclusionsThe magnitude of the shoulder region characteristic to GK cDVHs may be used to rapidly identify superior plan among candidates. Practical issues such as delivery time may require further consideration.

Indexed as

RadiosurgeryLinear ModelsRadiobiologyRadiotherapy DosageRadiotherapy Planning, Computer-Assisteddose-volume histogramequivalent uniform doseGamma Kniferadiosurgerytumor control probability

Identifiers

PMID32910543
PMCPMC7592963
OpenAlexW3084314061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.