ArticleJournal of neurovirology2020
Concurrent tonic pupil and trochlear nerve palsy in COVID-19.
Article in Journal of neurovirology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review.Medicine · 2022Pooled it
- Ross syndrome following COVID-19 infection in an 18-year-old Syrian male patient: a case report.Journal of medical case reports · 2025Article
- The Review of Ophthalmic Symptoms in COVID-19.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- Neurological complications after COVID-19: A narrative review.eNeurologicalSci · 2023Review
- Neuro-Ophthalmic Complications of COVID-19 Infection and Vaccination.Advances in ophthalmology and optometry · 2023Review
- Pupillographic Analysis of COVID-19 Patients: Early and Late Results After Recovery.Beyoglu eye journal · 2023Article
- Article
- Abnormal quantitative pupillary light responses following COVID-19.International ophthalmology · 2022Article
- How Does SARS-CoV-2 Affect Our Eyes-What Have We Learnt So Far about the Ophthalmic Manifestations of COVID-19?Journal of clinical medicine · 2022Review
- How to Manage a Strabismus Clinic During the COVID-19 Pandemic; What is Really Urgent, What is Not?: A Single-Center Case Series from TurkeyTurkish journal of ophthalmology · 2022Review
- Adie's Pupil: A Diagnostic Challenge for the Physician.Medical science monitor : international medical journal of experimental and clinical research · 2022Review
- Update on overview of ocular manifestations of COVID-19.Frontiers in medicine · 2022Review
- A Comparison of the Incidence and Type of Ocular Motility Defects in Patients Presenting to Birmingham Midland Eye Centre Emergency Department during 2019 and 2020 to Assess the Impact of the Covid-19 Pandemic.The British and Irish orthoptic journal · 2022Article
- COVID-19: Update on Its Ocular Involvements, and Complications From Its Treatments and Vaccinations.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) · 2021Review
- Clinical and Pathophysiologic Spectrum of Neuro-COVID.Molecular neurobiology · 2021Review
- [Tonic pupil after COVID-19 infection].Archivos de la Sociedad Espanola de Oftalmologia · 2021Article
- Tonic pupil after COVID-19 infection.Archivos de la Sociedad Espanola de Oftalmologia · 2021Article
- Internuclear ophthalmoplegia as a presenting feature in a COVID-19-positive patient.BMJ case reports · 2021Article
- Adie-Holmes syndrome associated with COVID-19 infection: A case report.Indian journal of ophthalmology · 2021Article
- Evidence of SARS-CoV-2 Transmission Through the Ocular Route.Clinical ophthalmology (Auckland, N.Z.) · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since COVID-19 was first reported, different neurological complications have been acknowledged, but their description is constantly evolving. We report a case of concurrent tonic pupil and trochlear nerve palsy in this context. A 62-year-old man reported a 5-day history of binocular vertical diplopia and blurred vision in his left eye, noticing that his left pupil was dilated. He had suffered a flu-like syndrome 2 weeks before. Clinical exam showed a right trochlear nerve palsy and a left mydriatic pupil. MRI, X chest ray, and analytical results were normal. Antibodies for SARS-CoV-2 were positive (low IgM and high IgG titers). Antiganglioside antibodies were negative. A 0.125% pilocarpine test confirmed Adie's pupil diagnosis. The patient was treated with a tapered prednisone dose with resolution of his diplopia but no change in Adie's pupil. This is the first case reporting Adie's pupil as a postinfectious manifestation of COVID-19. An immune-mediated mechanism is presumed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.