Evidence map›Paper›PMID 32910351›Full record

ArticleAIDS and behavior2021

Interest in Long-Acting Injectable Pre-exposure Prophylaxis (LAI PrEP) Among Women in the Women's Interagency HIV Study (WIHS): A Qualitative Study Across Six Cities in the United States.

Morgan M Philbin, Carrigan Parish, Elizabeth N Kinnard, Sarah E Reed, Deanna Kerrigan, Maria L Alcaide, Mardge H Cohen, Oluwakemi Sosanya, Anandi N Sheth, Adaora A Adimora and 5 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06133686 (Implementing Oral), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06133686 phase3not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan Africa: a Phase 3b, Open-label, Hybrid Type 2 Implementation and Effectiveness Trial

TypeinterventionalSponsorMRC/UVRI and LSHTM Uganda Research UnitRan2024 to 2027Enrolled400ConditionsHIVArmsTenofovir disoproxil fumarate/emtricitabine (TDF-FTC), cabotegravir (CAB-LA), Cabotegravir (CAB-LA), Tenofovir disoproxil fumarate/emtricitabine (TDF-FTC)
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Morgan M PhilbinDepartment of Sociomedical Sciences, Columbia University Mailman School of Public Health, New York, NY, USA. mp3243@columbia.edu.ORCID http://orcid.org/0000-0001-7608-7921
Carrigan ParishDepartment of Sociomedical Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Elizabeth N KinnardDepartment of Sociomedical Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Sarah E ReedDepartment of Sociomedical Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Deanna KerriganDepartment of Sociology, American University, Washington, D.C., USA.
Maria L AlcaideDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Mardge H CohenDepartments of Medicine/CORE Center at John H. Stroger, Cook County Health & Hospital System, Jr Hospital of Cook County, Chicago, IL, USA.
Oluwakemi SosanyaDepartment of Medicine, Montefiore, Bronx, NY, USA.
Anandi N ShethDepartment of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Adaora A AdimoraDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jennifer CocohobaDepartment of Clinical Pharmacy, University of California at San Francisco School of Pharmacy, UCSF, San Francisco, CA, USA.
Lakshmi GoparajuDepartment of Medicine, Georgetown University Medical Center, Washington, D.C., USA.
Elizabeth T GolubDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Margaret FischlDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Lisa R MetschDepartment of Sociomedical Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Columbia University · USUniversity of Miami · USAmerican University · USEmory University · USGeorgetown University · USJohns Hopkins University · USMontefiore Medical Center · USUniversity of California, San Francisco · USUniversity of North Carolina at Chapel Hill · US

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
SF Bay Area MACS/WIHS Combined Cohort StudyU01HL146242 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bradley E Aouizerat, Jennifer Cohen Price · 2019 to 2026
$36.3M
Sex differences in the role of multi-omicsin HIV-associated carotid artery atherosclerosisU01HL146193 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Stephen J Gange, Elizabeth Topper · 2019 to 2026
$35.8M
Sex differences in the role of multi-omics in HIV-associated carotid artery atherosclerosisU01HL146204 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI David B. Hanna, Anjali Sharma · 2019 to 2026
$33.2M
MACS/WIHS Combined Cohort Study Clinical Research SiteU01HL146241 · NHLBI · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Anandi Nayan Sheth · 2019 to 2026
$24.2M
Surviving the HIV Epidemic (S/HE) in metropolitan Washington DC - Advancing knowledge through cohort studiesU01HL146205 · NHLBI · GEORGETOWN UNIVERSITY · PI SEBLE G KASSAYE, DANIEL J MERENSTEIN · 2019 to 2026
$23.5M
MWCCS: The Chicago Cook County Clinical Research SiteU01HL146245 · NHLBI · HEKTOEN INSTITUTE FOR MEDICAL RESEARCH · PI Audrey French, Ryan Dee Ross · 2019 to 2026
$23.3M
UNC MACS/WIHS Combined Cohort Study Clinical Research SiteU01HL146194 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Michael Bradley Drummond, Michelle Floris-Moore · 2019 to 2026
$23.2M
Miami MACS-WIHS Combined Cohort Study Clinical Research SiteU01HL146203 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MARIA LUISA ALCAIDE, Deborah Lynne Jones · 2019 to 2026
$21.2M
Atlanta CRS U01-HL146241Atlanta/Emory Center for AIDS Research P30-AI-050409Bronx CRS U01-HL146204Center for AIDS Research, University of North Carolina at Chapel Hill P30-AI-050410Chicago-Cook County CRS HL146245Data Analysis and Coordination Center U01-HL146193Metropolitan Washington CRS U01-HL146205Miami CRS HL146203NCATS NIH HHS UL1 TR000004NHLBI NIH HHS U01 HL146193NHLBI NIH HHS U01 HL146194NHLBI NIH HHS U01 HL146203NHLBI NIH HHS U01 HL146204NHLBI NIH HHS U01 HL146205NHLBI NIH HHS U01 HL146241NHLBI NIH HHS U01 HL146242NHLBI NIH HHS U01 HL146245NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI051519NIDA NIH HHS K01 DA039804NIDA NIH HHS K01DA039804ANIDA NIH HHS L30 DA017071Northern California CRS U01-HL146242UCSF Clinical & Translational Science Institute UL1-TR000004
6 · The paper itself

Abstract

Long-acting injectable (LAI) pre-exposure prophylaxis (PrEP) has the potential to facilitate adherence and transform HIV prevention. However, little LAI PrEP research has occurred among women, who face unique barriers. We conducted 30 in-depth interviews with HIV-negative women from 2017-2018 across six sites (New York; Chicago; San Francisco; Atlanta; Washington, DC; Chapel Hill) of the Women's Interagency HIV Study. Interviews were recorded, transcribed, and analyzed using thematic content analysis. Few women expressed interest in PrEP and when prompted to choose a regimen, 55% would prefer LAI, 10% daily pills, and 33% said they would not take PrEP regardless of formulation. Perceived barriers included: (1) the fear of new-and perceived untested-injectable products and (2) potential side effects (e.g., injection-site pain, nausea). Facilitators included: (1) believing shots were more effective than pills; (2) ease and convenience; and (3) confidentiality. Future studies should incorporate women's LAI PrEP-related experiences to facilitate uptake.

Indexed as

AdultAgedAnti-HIV AgentsCitiesFemaleHIV InfectionsHumansInjectionsMiddle AgedPatient Acceptance of Health CarePatient PreferencePre-Exposure ProphylaxisQualitative ResearchUnited StatesAnti-HIV AgentsAIDSHIVLong-acting injectable (LAI)Pre-exposure prophylaxis (PrEP)PreventionQualitative researchWomen

Identifiers

PMID32910351
PMCPMC7886938
OpenAlexW3085786317

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.