Evidence map›Paper›PMID 32910322›Full record

ArticleInfection2021

Comparison of four commercial SARS-CoV-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings.

Jens T Van Praet, Ann-Sofie Coene, Kris Van De Moortele, Patrick Descheemaeker, Marijke Reynders

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jens T Van PraetDepartment of Nephrology and Infectious Diseases, AZ Sint-Jan Brugge-Oostende AV, Ruddershove 10, 8000, Brugge, Belgium. Jens.VanPraet@azsintjan.be.ORCID http://orcid.org/0000-0002-7125-7001
Ann-Sofie CoeneFaculty of Medicine, KU Leuven, Leuven, Belgium.
Kris Van De MoorteleDepartment of Radiology, AZ Sint-Jan Brugge-Oostende AV, Brugge, Belgium.
Patrick DescheemaekerDepartment of Laboratory Medicine, Medical Microbiology, AZ Sint-Jan Brugge-Oostende AV, Brugge, Belgium.
Marijke ReyndersDepartment of Laboratory Medicine, Medical Microbiology, AZ Sint-Jan Brugge-Oostende AV, Brugge, Belgium.
AZ Sint-Jan · BEKU Leuven · BEUniversity College Ghent · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A subset of patients with Covid-19 presents with negative RT-PCR screening but suspect CT findings. Using four commercially available anti-SARS-CoV-2 IgG immuno-assays, we found this subset constituted 9.2% of all consecutively admitted outpatients with Covid-19 in our hospital. Clinical specificity for Covid-19 of some N protein-based immuno-assays was suboptimal, as positive results were observed in control patients with recent common human coronavirus, influenza B and adenovirus infections.

Indexed as

Adenovirus Infections, HumanAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCoronavirus InfectionsCOVID-19COVID-19 TestingCross ReactionsEnzyme-Linked Immunosorbent AssayFalse Positive ReactionsFemaleHumansInfantCovid-19ELISASARS-CoV-2Serology

Identifiers

PMID32910322
PMCPMC7482374
OpenAlexW3084170816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.