ArticleMagma (New York, N.Y.)2021
Probing hepatic metabolism of [2-
Article in Magma (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Hyperpolarised magnetic resonance spectroscopy with lab-on-a-chip disease models.Disease models & mechanisms · 2026Review
- Hyperpolarized Carbon-13 Magnetic Resonance Imaging: Technical Considerations and Clinical Applications.Korean journal of radiology · 2024Review
- Hyperpolarized [1-Magnetic resonance in medicine · 2024Article
- Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies.Magnetic resonance letters · 2023Review
- Magnetic Resonance Imaging and Spectroscopy Methods to Study Hepatic Glucose Metabolism and Their Applications in the Healthy and Diabetic Liver.Metabolites · 2022Review
- Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities.Liver international : official journal of the International Association for the Study of the Liver · 2022Review
- Solution Chemistry of Dihydroxyacetone and Synthesis of Monomeric Dihydroxyacetone.Chemical research in toxicology · 2022Article
- Non-Invasive Analysis of Human Liver Metabolism by Magnetic Resonance Spectroscopy.Metabolites · 2021Review
- Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State.Metabolites · 2021Article
- Comprehensive Literature Review of Hyperpolarized Carbon-13 MRI: The Road to Clinical Application.Metabolites · 2021Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesTo enhance detection of the products of hyperpolarized [2-
methodsReal-time hepatic metabolism of three fed mice was probed by
resultsThe metabolic products detected in vivo include glycerol 3-phosphate, glycerol, phosphoenolpyruvate, lactate, alanine, glyceraldehyde 3-phosphate and glucose 6-phosphate. The metabolite-to-substrate ratios were comparable to those reported previously in perfused liver. DISCUSSION: Three metabolic pathways can be probed simultaneously in the mouse liver in vivo, in real time, using hyperpolarized DHAc.
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Registered trials
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