SynthesisPediatric radiology2021
Early life ionizing radiation exposure and cancer risks: systematic review and meta-analysis.
Synthesis in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Ionizing radiation exposure during adulthood and risk of developing central nervous system tumors: systematic review and meta-analysis.Scientific reports · 2022Pooled it
- The impact of hospital volume on CT usage in the management of pediatric empyema.Pediatric surgery international · 2026Article
- Cumulative dose in pediatric CT "frequent flyers": cohort results and risk review.Pediatric radiology · 2026Article
- Radiation Dose Evaluation in Pediatric Patients Undergoing Repeated Brain Computed Tomography Examinations.Diagnostics (Basel, Switzerland) · 2026Article
- Sociodemographic factors associated with public awareness of medical radiation risks and safety practices in the West Bank, Palestine: a cross-sectional study.BMC public health · 2026Article
- Utilization of Imaging in Young Athletes with Low Back Pain.International journal of sports physical therapy · 2026Article
- Patient knowledge and acceptance of radiation safety measures correlated to actual exposure records: A survey study.Bioinformation · 2026Article
- Limited immune perturbations in mice exposed to sustained low-dose ionizing radiation.Frontiers in immunology · 2026Article
- Pediatric pulmonary nodules: current state of knowledge, AI applications, and future directions.Pediatric radiology · 2026Review
- High performance of low/ultralow-dose photon-counting CT for pulmonary metastasis in young musculoskeletal malignancy patients.European journal of radiology open · 2025Article
- Medical Imaging and Pediatric and Adolescent Hematologic Cancer Risk.The New England journal of medicine · 2025Article
- Radiation Exposure During Contrast-Enhanced Videofluoroscopic Swallow Studies in Dogs and Cats.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2025Article
- Causes of Childhood Cancer: A Review of Literature (2014-2021): Part 2-Pregnancy and Birth-Related Factors.Cancers · 2025Review
- Establishing Diagnostic Reference Levels for Paediatric CT Imaging: A Multi-Centre Study.Healthcare (Basel, Switzerland) · 2025Article
- Gamma radiation detector selection for CT scanner.Zeitschrift fur medizinische Physik · 2025Article
- Are Routine Post-Cast Removal Radiographs and a Second Follow-up Appointment Necessary in the Management of Nondisplaced or Minimally Displaced Distal Radius Fractures?Journal of the Pediatric Orthopaedic Society of North America · 2025Article
- Expert panel on monitoring radiation doses from recurrent medical diagnostic procedures: Sixth Gilbert W. Beebe Webinar.Journal of applied clinical medical physics · 2025Review
- AI-Driven Advances in Low-Dose Imaging and Enhancement-A Review.Diagnostics (Basel, Switzerland) · 2025Review
- Do urologists actually comply with the ALARA principle in pediatric urolithiasis management?Urolithiasis · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIonizing radiation use for medical diagnostic purposes has substantially increased over the last three decades. Moderate to high doses of radiation are well established causes of cancer, especially for exposure at young ages. However, cancer risk from low-dose medical imaging is debated.
objectiveTo review the literature on cancer risks associated with prenatal and postnatal medical diagnostic ionizing radiation exposure among children and to assess this risk through a meta-analysis. MATERIALS AND
methodsA literature search of five electronic databases supplemented by a hand search was performed to retrieve relevant epidemiological studies published from 2000 to 2019, including patients younger than 22 years of age exposed to medical imaging ionizing radiation. Pooled odds ratio (OR
resultsTwenty-four studies were included. For prenatal exposure (radiographs or CT), no significant increased risk was reported for all cancers, leukemia and brain tumors. For postnatal exposure, increased risk was observed only for CT, mostly for leukemia (ERR
conclusionCT exposure in childhood appears to be associated with increased risk of cancer while no significant association was observed with diagnostic radiographs.
Indexed as
Identifiers
32910229What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.