Evidence map›Paper›PMID 32910061›Full record

ArticleAIDS (London, England)2020

Associations between methamphetamine use and lack of viral suppression among a cohort of HIV-positive persons who inject drugs in Hai Phong, Vietnam.

Jonathan Feelemyer, Kamyar Arasteh, Duong T Huong, Khuat T H Oanh, Pham M Khue, Hoang T Giang, Nham T T Thanh, Jean Pierre Moles, Vu H Vinh, Roselyne Vallo and 8 more

Open access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
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  5. Article
  6. Perspectives on addiction-related problems in Vietnam.Addiction (Abingdon, England) · 2026
    Review
  7. Article
  8. Article
  9. Overamped: Stimulant Use and HIV Pathogenesis.Current HIV/AIDS reports · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Cognitive Phenotypes of HIV Defined Using a Novel Data-driven Approach.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 3 countries.

Jonathan FeelemyerNew York University College of Global Public Health, New York, New York, USA.
Kamyar ArastehNew York University College of Global Public Health, New York, New York, USA.
Duong T HuongHaiphong University of Medicine and Pharmacy, Hai Phong.
Khuat T H OanhSupporting Community Development Initiatives, Hanoi, Vietnam.
Pham M KhueHaiphong University of Medicine and Pharmacy, Hai Phong.
Hoang T GiangHaiphong University of Medicine and Pharmacy, Hai Phong.
Nham T T ThanhSupporting Community Development Initiatives, Hanoi, Vietnam.
Jean Pierre MolesInserm U1058, Etablissement Français du Sang, University of Montpellier, Montpellier, France.
Vu H VinhDepartment of Infectious and Tropical Diseases, Viet Tiep Hospital, Haiphong, Vietnam.
Roselyne ValloInserm U1058, Etablissement Français du Sang, University of Montpellier, Montpellier, France.
Catherine QuilletInserm U1058, Etablissement Français du Sang, University of Montpellier, Montpellier, France.
Delphine RapoudInserm U1058, Etablissement Français du Sang, University of Montpellier, Montpellier, France.
Sao M LeHaiphong University of Medicine and Pharmacy, Hai Phong.
Laurent MichelPierre Nicole Center, French Red Cross, CESP/Inserrm 1018, Paris.
Didier LaureillardInserm U1058, Etablissement Français du Sang, University of Montpellier, Montpellier, France.
Nicolas NagotInserm U1058, Etablissement Français du Sang, University of Montpellier, Montpellier, France.
Don C Des JarlaisNew York University College of Global Public Health, New York, New York, USA.
DRIVE STUDY TEAM
Hai phong University Of Medicine and Pharmacy · VNNew York University · USUniversité de Montpellier · FRCenter for Creative Initiatives in Health and Population · VNInserm · FRCentre de recherche en Epidémiologie et Santé des Populations · FRÉtablissement Français du Sang · FRHung Vuong Hospital · VN

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan, Courtney McKnight · 1998 to 2026
$38.9M
DRIVE (DRug use and blood-borne Infections in ViEtnam): Combined prevention and care to end the HIV epidemic among people who inject drugs in Haiphong, Viet NamR01DA041978 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C · 2016 to 2020
$4.9M
NIDA NIH HHS R01 DA041978
6 · The paper itself

Abstract

objectiveWe assessed the association between methamphetamine use and lack of viral suppression among a cohort of HIV-seropositive persons who inject drugs (PWID) in Hai Phong, Vietnam.

designCohort study with random effects logit modeling and mediation analysis for antiretroviral therapy (ART) adherence.

methodsPWID were recruited from October 2016 to October 2017; HIV-seropositive PWID were enrolled in a cohort to assess HIV viral loads, changes in drug use, risk behaviors, and ART adherence during 24-month follow-up. Methamphetamine use in last 30 days was divided into three categories: 0 days (no use), 1-19 days (intermediate), and 20 or more days (heavy). Bivariate and a multivariable random effects logit models were used to assess the relationship between methamphetamine use and not being virally suppressed. We also assessed self-reported ART adherence as a mediating factor.

resultsA total of 645 HIV-seropositive PWID were included at baseline; 95% male, average age 40 (SD = 6.4). At baseline, methamphetamine use in last 30 days was 64% no use, 32% intermediate use, 4% heavy use. Approximately 74% of PWID reported high/complete adherence; 76% were at viral suppression. In random effects analysis, recent methamphetamine use was associated with not being virally suppressed during follow-up (adjusted odds ratio: 1.84, 95% confidence interval: 1.06, 3.17); the effect was not explained by a mediating effect of self-reported adherence to ART.

conclusionRecent methamphetamine use is associated with not being virally suppressed among PWID. The results of this study indicate the need for targeted interventions for methamphetamine use with special focus on those with HIV infection.

Indexed as

HIV InfectionsAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCohort StudiesDrug MonitoringDrug UsersFemaleHumansMaleMethamphetamineMiddle AgedRisk-TakingSubstance Abuse, IntravenousTreatment Adherence and ComplianceTreatment OutcomeAnti-HIV AgentsMethamphetamine

Identifiers

PMID32910061
PMCPMC7584399
OpenAlexW3084271729

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.