Evidence map›Paper›PMID 32910024›Full record

Observational studyRetinal cases & brief reports2022

SPONTANEOUS LAMELLAR MACULAR HOLES CLOSURE.

Ismael Chehaibou, Niranjan Manoharan, Andrea Govetto, Irena Tsui, Jean-Pierre Hubschman

Open access · greenAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Retinal cases & brief reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Primary Lamellar Macular Holes: To Vit or Not to Vit.Journal of clinical medicine · 2022
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Ismael ChehaibouRetina Division, Stein Eye Institute, University of California Los Angeles, Los Angeles, California.
Niranjan ManoharanRetina Division, Stein Eye Institute, University of California Los Angeles, Los Angeles, California.
Andrea GovettoOphthalmology Department, Fatebenefratelli-Oftalmico Hospital, ASST-Fatebenefratelli-Sacco, Milan, Italy.
Irena TsuiRetina Division, Stein Eye Institute, University of California Los Angeles, Los Angeles, California.
Jean-Pierre HubschmanRetina Division, Stein Eye Institute, University of California Los Angeles, Los Angeles, California.
University of California, Los Angeles · USAssistance Publique – Hôpitaux de Paris · FRASST Fatebenefratelli Sacco · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report two cases of spontaneous closure of lamellar macular holes with epiretinal proliferation (ERP).

methodsObservational cases report.

resultsTwo patients affected with lamellar macular hole showed progressive and spontaneous closure of the hole associated with ERP development. At presentation, both patients presented with irregular foveal contour, and foveal cavitation with apparent loss of retinal tissue. In both cases, ERP, also called "lamellar hole-associated epiretinal proliferation", was present and increased in size over time. This proliferation progressively developed across the hole with apparent restoration of the foveal contour and preservation of visual acuity.

conclusionThis report describes two cases of lamellar macular hole in which ERP increased over time, resulting in lamellar macular hole closure. Such observations may suggest a spontaneous healing process driven by glial cell proliferation.

Indexed as

Epiretinal MembraneRetinal PerforationsFollow-Up StudiesHumansRetrospective StudiesTomography, Optical CoherenceVisual AcuityVitrectomy

Identifiers

PMID32910024
OpenAlexW3084252826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.