Evidence map›Paper›PMID 32909603›Full record

SynthesisJournal of pediatric psychology2020

A Systematic Review of External Validity in Pediatric Integrated Primary Care Trials.

Alicia Callejo-Black, David V Wagner, Krishnapriya Ramanujam, Ann Jeline Manabat, Sarah Mastel, Andrew R Riley

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of pediatric psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alicia Callejo-BlackSchool of Medicine, University of California-San Diego.
David V WagnerDepartment of Pediatrics, Institute on Development & Disability, Oregon Health & Science University, Portland, Oregon.
Krishnapriya RamanujamDepartment of Pediatrics, Institute on Development & Disability, Oregon Health & Science University, Portland, Oregon.
Ann Jeline ManabatPortland State University.
Sarah MastelDepartment of Pediatrics, Institute on Development & Disability, Oregon Health & Science University, Portland, Oregon.
Andrew R RileyDepartment of Pediatrics, Institute on Development & Disability, Oregon Health & Science University, Portland, Oregon.
Oregon Health & Science University · USPortland State University · USUniversity of California San Diego · US

Funding

EXITO: Enhancing Cross-disciplinary Infrastructure and Training at OregonUL1GM118964 · NIGMS · PORTLAND STATE UNIVERSITY · PI KELLER, THOMAS E · 2015 to 2023
$18.0M
EXITO: Enhancing Cross-disciplinary Infrastructure and Training at OregonRL5GM118963 · NIGMS · PORTLAND STATE UNIVERSITY · PI KELLER, THOMAS E · 2015 to 2023
$11.9M
EXITO: Enhancing Cross-disciplinary Infrastructure and Training at OregonTL4GM118965 · NIGMS · PORTLAND STATE UNIVERSITY · PI KELLER, THOMAS E · 2015 to 2022
$10.1M
Oregon Patient Centered Outcomes Research K12 ProgramK12HS022981 · AHRQ · OREGON HEALTH & SCIENCE UNIVERSITY · PI GUISE, JEANNE-MARIE · 2014 to 2018
$4.1M
AHRQ HHS K12 HS022981NIGMS NIH HHS RL5 GM118963NIGMS NIH HHS TL4 GM118965NIGMS NIH HHS UL1 GM118964
6 · The paper itself

Abstract

objectiveWe used the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework to conduct a systematic review of external validity reporting in integrated primary care (IPC) interventions for mental health concerns.

methodsWe searched Medline, CINAHL, PsycINFO, the Cochrane Center Register of Controlled Trials, and relevant literature to identify publications from 1998 to 2018 reporting on open, randomized, or quasi-randomized trials of IPC interventions that targeted child (ages 0-18 years) psychological symptoms. For each publication, we extracted the information reported in each RE-AIM domain and calculated the proportion of the total studies reviewed.

resultsThirty-nine publications describing 25 studies were included in the review. Publications rarely reported some indicators of external validity, including the representativeness of participants (12%), rate of adoption clinics or providers (16%), cost of implementation (8%), or evidence of maintenance (16%). Few studies reported on key pragmatic factors such as cost or organizational change processes related to implementation and maintenance. Strengths of some studies included comparisons of multiple active treatments, use of tailorable interventions, and implementation in "real world" settings.

conclusionsAlthough IPC interventions appear efficacious under research conditions, there are significant knowledge gaps regarding the degree to which they reach and engage target recipients, what factors impact adoption and implementation of IPC interventions by clinicians, how fidelity can be maintained over time, and cost-effectiveness. Pediatric IPC researchers should embrace dissemination and implementation science methods to balance internal and external validity concerns moving forward.

Indexed as

Mental HealthPrimary Health CareAdolescentChildChild, PreschoolCost-Benefit AnalysisHumansInfantInfant, Newbornhealthcare servicesintegrated caremental healthprimary careresearch designs and methodssystematic review

Identifiers

PMID32909603
PMCPMC8202128
OpenAlexW3086304326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.