Evidence map›Paper›PMID 32909535›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Case Report: Lung Ultrasound for the Guidance of Adjunctive Therapies in Two Invasively Ventilated Patients with COVID-19.

Charalampos Pierrakos, Rachid Attou, Enrica Iesu, Hugues Baelongandi, Patrick M Honore, Lieuwe D J Bos, Marcus J Schultz, David De Bels

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Charalampos PierrakosDepartment of Intensive Care, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Rachid AttouDepartment of Intensive Care, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Enrica IesuDepartment of Anesthesiology, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Hugues BaelongandiDepartment of Anesthesiology, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Patrick M HonoreDepartment of Intensive Care, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Lieuwe D J BosDepartment of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Marcus J SchultzLaboratory of Experimental Intensive Care and Anesthesiology (LEICA), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
David De BelsDepartment of Intensive Care, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Université Libre de Bruxelles · BEAmsterdam University Medical Centers · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two patients with respiratory failure due to confirmed COVID-19 were examined using bedside lung ultrasound (LUS) shortly after intubation and start of invasive ventilation. In the first patient, LUS revealed extensive atelectatic areas. A recruitment maneuver was applied, resulting in some reaeration of areas that showed atelectasis, and some improvement in oxygenation was observed. Oxygenation improved further with the use of prone positioning. In the second patient, LUS showed diffuse abnormalities without atelectatic areas, and ventilation proceeded without a recruitment maneuver but with prone positioning. These two cases illustrate how LUS could be useful in identifying different lung morphologies early after the start of invasive ventilation and help decide on adjunctive therapies. This has possible implications for ventilator management in resource-limited settings, with limited availability of chest computed tomography and blood gas analyzers. Tailoring invasive ventilation based on LUS findings early after the start of invasive ventilation is feasible, but this should be further evaluated in future studies.

Indexed as

UltrasonographyAgedBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansLungMaleMiddle AgedPandemicsPneumonia, ViralProne PositionRespiration, ArtificialSARS-CoV-2Tomography, X-Ray Computed

Identifiers

PMID32909535
PMCPMC7646794
OpenAlexW3084919601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.