Evidence map›Paper›PMID 32909347›Full record

ArticleChembiochem : a European journal of chemical biology2021

Building up Pt

Alexander Haseloer, Tamara Lützenburg, Joss Pepe Strache, Jörg Neudörfl, Ines Neundorf, Axel Klein

Open access · hybridAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Building up PtChembiochem : a European journal of chemical biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexander HaseloerUniversität zu Köln, Department für Chemie, Institut für Anorganische Chemie, Greinstraße 6, 50939, Köln, Germany.ORCID 0000-0003-0480-7568
Tamara LützenburgUniversität zu Köln, Department für Chemie, Institut für Biochemie, Zülpicher Strasse 47a, 50674, Köln, Germany.ORCID 0000-0003-0629-4022
Joss Pepe StracheUniversität zu Köln, Department für Chemie, Institut für Anorganische Chemie, Greinstraße 6, 50939, Köln, Germany.ORCID 0000-0001-7321-8375
Jörg NeudörflUniversität zu Köln, Department für Chemie, Institut für Organische Chemie, Greinstraße 4, 50939, Köln, Germany.ORCID 0000-0002-2918-0565
Ines NeundorfUniversität zu Köln, Department für Chemie, Institut für Biochemie, Zülpicher Strasse 47a, 50674, Köln, Germany.ORCID 0000-0001-6450-3991
Axel KleinUniversität zu Köln, Department für Chemie, Institut für Anorganische Chemie, Greinstraße 6, 50939, Köln, Germany.ORCID 0000-0003-0093-9619
University of Cologne · DE

Funding

Cologne University ClinicsDepartment of ChemistryInstitute for Nuclear ChemistryInstitute of RadiochemistryJürgen-Manchot StiftungResearch Center Jülich
6 · The paper itself

Abstract

Three chiral tridentate N^N^S coordinating pyridine-carbaldehyde (S)-N4-(α-methylbenzyl)thiosemicarbazones (HTSCmB) were synthesised along with lysine-modified derivatives. One of them was selected and covalently conjugated to the cell-penetrating peptide sC18 by solid-phase peptide synthesis. The HTSCmB model ligands, the HTSCLp derivatives and the peptide conjugate rapidly and quantitatively form very stable Pt

Indexed as

Cell-Penetrating PeptidesHumansLysineOrganometallic CompoundsPeptide FragmentsPlatinumThiosemicarbazonesCell-Penetrating PeptidesLysineOrganometallic CompoundsPeptide FragmentsPlatinumThiosemicarbazonesAntiproliferativecell-penetrating peptidesconjugatesplatinumthiosemicarbazone

Identifiers

PMID32909347
PMCPMC7894172
OpenAlexW3084065461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.