Evidence map›Paper›PMID 32909136›Full record

ArticleEuropean journal of nutrition2021

Omega-3 fatty acid intake and decreased risk of skin cancer in organ transplant recipients.

Kyoko Miura, Mandy Way, Zainab Jiyad, Louise Marquart, Elsemieke I Plasmeijer, Scott Campbell, Nicole Isbel, Jonathan Fawcett, Lisa E Ferguson, Marcia Davis and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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  7. Daily Lifestyle and Cutaneous Malignancies.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Kyoko MiuraPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia. Kyoko.Miura@qimrberghofer.edu.au.ORCID http://orcid.org/0000-0002-2805-7522
Mandy WayPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia.ORCID http://orcid.org/0000-0003-3444-1907
Zainab JiyadPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia.ORCID http://orcid.org/0000-0001-9677-8885
Louise MarquartStatistics Unit, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.ORCID http://orcid.org/0000-0003-4607-9060
Elsemieke I PlasmeijerPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia.ORCID http://orcid.org/0000-0002-8846-1930
Scott CampbellDepartment of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0003-1338-2151
Nicole IsbelDepartment of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0002-9566-7179
Jonathan FawcettQueensland Liver Transplant Service, University of Queensland, Princess Alexandra Hospital, Brisbane, QLD, Australia.
Lisa E FergusonPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia.ORCID http://orcid.org/0000-0002-3469-6419
Marcia DavisPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia.ORCID http://orcid.org/0000-0001-5632-7801
David C WhitemanPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia.ORCID http://orcid.org/0000-0003-2563-9559
H Peter SoyerDermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Woolloongabba, QLD, Australia.ORCID http://orcid.org/0000-0002-4770-561X
Peter O'RourkeStatistics Unit, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.ORCID http://orcid.org/0000-0001-9794-2122
Adèle C GreenPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, Australia.ORCID http://orcid.org/0000-0002-2753-4841
QIMR Berghofer Medical Research Institute · AUThe University of Queensland · AUQueensland University of Technology · AUSt George's, University of London · GB

Funding

National Health and Medical Research Council of Australia 1073898National Health and Medical Research Council of Australia 552429National Health and Medical Research Council of Australia APP1040947National Health and Medical Research Council of Australia APP1058522National Health and Medical Research Council of Australia APP1155413
6 · The paper itself

Abstract

purposeOrgan transplant recipients have over 100-fold higher risk of developing skin cancer than the general population and are in need of further preventive strategies. We assessed the possible preventive effects of omega-3 polyunsaturated fatty acid (PUFA) intake from food on the two main skin cancers, squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) in kidney and liver transplant recipients.

methodsAdult kidney or liver transplant recipients transplanted for at least 1 year and at high risk of skin cancer were recruited from the main transplant hospital in Queensland, 2012-2014 and followed until mid-2016. We estimated their dietary total long-chain omega-3 PUFAs and α-linolenic acid intakes at baseline using a food frequency questionnaire and ranked PUFA intakes as low, medium, or high. Relative risks (RRs

resultsThere were 449 transplant recipients (mean age, 55 years; 286 (64%) male). During follow-up, 149 (33%) patients developed SCC (median 2/person; range 1-40) and 134 (30%), BCC. Transplant recipients with high total long-chain omega-3 PUFA compared with low intakes showed substantially reduced SCC tumour risk (RR

conclusionAmong organ transplant recipients, relatively high intakes of long-chain omega-3 PUFAs and of α-linolenic acid may reduce risks of SCC and BCC, respectively.

Indexed as

Fatty Acids, Omega-3Organ TransplantationSkin NeoplasmsAdultFollow-Up StudiesHumansIncidenceMaleMiddle AgedQueenslandTransplant RecipientsFatty Acids, Omega-3Alpha-linolenic acidCohort studiesOmega-3 fatty acidsOrgan transplantationSkin neoplasms

Identifiers

PMID32909136
OpenAlexW3085264923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.