ArticleCerebral cortex (New York, N.Y. : 1991)2021
A Whole-Brain and Cross-Diagnostic Perspective on Functional Brain Network Dysfunction.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 37 citations in OpenAlex.
- An Epicenter-guided computational framework for personalized target of repetitive transcranial magnetic stimulation in schizophrenia.NeuroImage. Clinical · 2026Article
- Modeling Complex Effects and Individual Variability in Multi-Paradigm fMRI with Nonlinear Mixed Models.bioRxiv : the preprint server for biology · 2026Article
- Examining anterior prefrontal cortex resting-state functional connectivity patterns associated with depressive symptoms in chronic moderate-to-severe traumatic brain injury.Frontiers in neurology · 2025Article
- Improved whole-brain reconfiguration efficiency reveals mechanisms of speech rehabilitation in cleft lip and palate patients: an fMRI study.Frontiers in aging neuroscience · 2025Article
- Acute psychosocial stress modulates neural and behavioral substrates of cognitive control.Human brain mapping · 2024Article
- Static and dynamic brain functional connectivity patterns in patients with unilateral moderate-to-severe asymptomatic carotid stenosis.Frontiers in aging neuroscience · 2024Article
- The impact of functional correlations on task information coding.Network neuroscience (Cambridge, Mass.) · 2024Article
- Identifying Replicable Subgroups in Neurodevelopmental Conditions Using Resting-State Functional Magnetic Resonance Imaging Data.JAMA network open · 2023Article
- Dorsal attention network activity during perceptual organization is distinct in schizophrenia and predictive of cognitive disorganization.The European journal of neuroscience · 2023Article
- Controversies and progress on standardization of large-scale brain network nomenclature.Network neuroscience (Cambridge, Mass.) · 2023Article
- Investigating heterogeneity across autism, ADHD, and typical development using measures of cortical thickness, surface area, cortical/subcortical volume, and structural covariance.Frontiers in child and adolescent psychiatry · 2023Article
- The topology, stability, and instability of learning-induced brain network repertoires in schizophrenia.Network neuroscience (Cambridge, Mass.) · 2023Article
- Scan Once, Analyse Many: Using Large Open-Access Neuroimaging Datasets to Understand the Brain.Neuroinformatics · 2022Article
- Retained Primitive Reflexes and Potential for Intervention in Autistic Spectrum Disorders.Frontiers in neurology · 2022Review
- Attention for Emotion-How Young Adults With Neurodevelopmental Disorders Look at Facial Expressions of Affect.Frontiers in psychiatry · 2022Article
- The brain and its time: intrinsic neural timescales are key for input processing.Communications biology · 2021Review
- Brain network mechanisms of visual shape completion.NeuroImage · 2021Article
- Activity flow underlying abnormalities in brain activations and cognition in schizophrenia.Science advances · 2021Article
- Predicting dysfunctional age-related task activations from resting-state network alterations.NeuroImage · 2020Article
- Accurate prediction of individual subject identity and task, but not autism diagnosis, from functional connectomes.Human brain mapping · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
A wide variety of mental disorders have been associated with resting-state functional network alterations, which are thought to contribute to the cognitive changes underlying mental illness. These observations appear to support theories postulating large-scale disruptions of brain systems in mental illness. However, existing approaches isolate differences in network organization without putting those differences in a broad, whole-brain perspective. Using a graph distance approach-connectome-wide similarity-we found that whole-brain resting-state functional network organization is highly similar across groups of individuals with and without a variety of mental diseases. This similarity was observed across autism spectrum disorder, attention-deficit hyperactivity disorder, and schizophrenia. Nonetheless, subtle differences in network graph distance were predictive of diagnosis, suggesting that while functional connectomes differ little across health and disease, those differences are informative. These results suggest a need to reevaluate neurocognitive theories of mental illness, with a role for subtle functional brain network changes in the production of an array of mental diseases. Such small network alterations suggest the possibility that small, well-targeted alterations to brain network organization may provide meaningful improvements for a variety of mental disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.