Evidence map›Paper›PMID 32908856›Full record

ArticleInternational journal of genomics2020

Comparative Metabolomics Study Revealed Difference in Central Carbon Metabolism between Sika Deer and Red Deer Antler.

Hang Su, Chonghui Yang, Chenrong Jin, He Zhang, Chengcheng Yin, Yang Yang, Haoyuan Chen, Li Jing, Bin Qi, Daqing Zhao and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Hang SuPractice Innovations Center, Changchun University of Chinese Medicine, Changchun 130117, China.
Chonghui YangJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Chenrong JinCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
He ZhangResearch Center of Traditional Chinese Medicine, College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID https://orcid.org/0000-0002-2891-8687
Chengcheng YinCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
Yang YangCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
Haoyuan ChenCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
Li JingPractice Innovations Center, Changchun University of Chinese Medicine, Changchun 130117, China.
Bin QiCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
Daqing ZhaoJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID https://orcid.org/0000-0001-5678-7410
Xueyuan BaiJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID https://orcid.org/0000-0001-8605-4955
Li LiuCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID https://orcid.org/0000-0002-6645-1352
Changchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antler regeneration has been well studied for the past two decades and adopted in the regenerative medicine model for studying on developmental biology. Despite our growing knowledge of functional molecules regulating antler regeneration, we still do not know whether antler from different deer species possess the exact same mechanism or not. Our previous comparative study between sika deer and red deer suggests that the metabolic pathways between them are profoundly different based on protein level. Therefore, the metabolomic technology is used to identify and quantify the metabolites in antler samples, providing interesting insights into differential metabolite profile of antlers between sika deer and red deer. The distinct metabolic characteristics of sika deer compared to red deer provide an opportunity to explain why the red deer antler with a larger size. The enrichment analysis of differential metabolites showed that three pathways including glycine and serine metabolism, methionine metabolism, and pterine biosynthesis had a significant difference between two antler groups.

Identifiers

PMID32908856
PMCPMC7471787
OpenAlexW3081272218

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.