Evidence map›Paper›PMID 32908577›Full record

ArticleComputational and mathematical methods in medicine2020

lncRNA-SNHG14 Promotes Atherosclerosis by Regulating ROR

Baoliang Zhu, Jing Liu, Ying Zhao, Jing Yan

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Role of LncRNAs in the Pathogenesis of Coronary Artery Disease.Reviews in cardiovascular medicine · 2023
    Review
  3. Review
  4. Retracted: lncRNA-SNHG14 Promotes Atherosclerosis by Regulating RORComputational and mathematical methods in medicine · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. lncRNAInternational journal of clinical and experimental pathology · 2021
    Article
  9. Article
  10. Dysregulation Serum miR-19a-3p is a Diagnostic Biomarker for Asymptomatic Carotid Artery Stenosis and a Promising Predictor of Cerebral Ischemia Events.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Baoliang ZhuDepartment of Physiology, Jining Medical College, Jining, Shandong, China.
Jing LiuDepartment of Pharmacy, Jining Medical College, Jining, Shandong, China.
Ying ZhaoDepartment of Biochemistry, Jining Medical College, Jining, Shandong, China.
Jing YanDepartment of Physiology, Jining Medical College, Jining, Shandong, China.ORCID https://orcid.org/0000-0002-5202-3146
Jining Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary heart disease (CHD) is the most common cardiovascular disease with high prevalence, disability, and mortality. The balance between proliferation and apoptosis of vascular smooth muscle cells (VSMCs) plays a key role in the initiation of atherosclerosis. In this study, we found a significant decrease in the expression of lncRNA-SNHG14 in atherosclerotic plaque tissues of ApoE-/- mice. Overexpression of lncRNA-SNHG14 can inhibit VSMC proliferation while promoting apoptosis. There is a potential reciprocal regulatory relationship between lncRNASNHG14 and miR-19a-3p, which inhibit each other's expression in vascular smooth muscle cells. In addition, the luciferase reporter gene analysis results showed that there was a direct interaction between miR-19a-3p and the 3'UTR of ROR

Indexed as

3' Untranslated RegionsAnimalsApoptosisAtherosclerosisCell ProliferationCells, CulturedComputational BiologyDisease Models, AnimalGene Expression RegulationHumansMaleMathematical ConceptsMiceMice, Inbred C57BLMice, Knockout, ApoEMicroRNAs3' Untranslated RegionsMicroRNAsMIRN19a microRNA, mouseNuclear Receptor Subfamily 1, Group F, Member 1RNA, Long NoncodingRNA, MessengerRora protein, mouse

Identifiers

PMID32908577
PMCPMC7468621
OpenAlexW3081507554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.