ArticleNature2020
A protein assembly mediates Xist localization and gene silencing.
Erratum issuedAbstract read
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Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 122 papers.
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122citing papers in PubMed
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
122 citing papers in PubMed.
- Ptbp1 Condensates With Phase Separation-Like Features in Cardiomyocyte Nuclei Regulate Splicing of Proliferative Genes in Neonatal Cardiomyocytes.Development, growth & differentiation · 2026Article
- A continuum-based reaction-diffusion model for spread of gene silencing in chromosomal inactivation.RNA (New York, N.Y.) · 2026Article
- From inactivation to intervention: X chromosome silencing in disease pathogenesis and emerging therapeutic strategies.Genes & diseases · 2026Review
- Scanning transcriptomes for nonlinear, domain-level similarities using hmSEEKR.bioRxiv : the preprint server for biology · 2026Article
- Review
- FISH+ is a ready-to-use proximity labeling method for simultaneous RNA visualization and RNA-interacting protein identification.Communications biology · 2026Article
- lncRNA-operated stem cell fate control: RPS3 mediates the in situ Gm16751-Zhx3 interactome to program spermatogonial stem cell differentiation.Cell & bioscience · 2026Article
- Noncoding RNAs are indispensable architects and regulators of biomolecular condensates.Non-coding RNA research · 2026Review
- Correlated protein-RNA associations and a requirement for HNRNPU in the long-range recruitment of Polycomb Repressive Complexes by the lncRNAs Airn and Kcnq1ot1.PLoS genetics · 2026Article
- In situ proximity labeling of proteins associated with circRNA and RNA G-quadruplexes.Nature chemical biology · 2026Article
- Reprogramming the inactive X chromosome: dynamics and insights from the germline.Biochemical Society transactions · 2026Review
- Modification of internal RNA domains from the long non-coding RNA XIST refines roles in silencing and heterochromatin recruitment.Human molecular genetics · 2026Article
- Establishment and Maintenance of Repressed Chromatin States on Dosage-Compensated Sex Chromosomes.Biomolecules · 2026Review
- Multi-layered gene regulation by long non-coding RNAs: from chromatin to genome architecture.BMB reports · 2026Review
- Mechanisms at the Intersection of lncRNA and m6A Biology.Non-coding RNA · 2026Review
- Lyonization of X-chromosome: New insights.Journal of genetics · 2026Review
- Xist in X chromosome inactivation: mechanisms and disease relevance.Cell communication and signaling : CCS · 2025Review
- Impact of somatic XIST deletions on ongoing XIST expression and inactive X silencing and heterochromatin.Human molecular genetics · 2025Article
- Heterochromatome wide analyses reveal MBD2 as a phase separation scaffold for heterochromatin compartmentalization and composition.Nucleic acids research · 2025Article
- Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
18 authors.
Amy Pandya-JonesDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-5519-4613
Yolanda MarkakiDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Jacques SerizayDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-4295-0624
Tsotne ChitiashviliDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Walter R Mancia LeonDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1920-6514
Andrey DamianovDepartment of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, USA.
Constantinos ChronisDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Bernadett PappDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-5352-3946
Chun-Kan ChenDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Robin McKeeDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Xiao-Jun WangDepartment of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, USA.
Anthony ChauDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Shan SabriDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Heinrich LeonhardtDepartment of Biology and Center for Integrated Protein Science, LMU Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-5086-6449
Sika ZhengDepartment of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, USA.
Mitchell GuttmanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Douglas L BlackDepartment of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, USA. dougb@microbio.ucla.edu.ORCID http://orcid.org/0000-0002-2705-8187
Kathrin PlathDepartment of Biological Chemistry at the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA. kplath@mednet.ucla.edu.ORCID http://orcid.org/0000-0001-7796-3372
Funding
Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5MThe Regulation of Neuronal Exon SplicingR01GM049662 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BLACK, DOUGLAS L · 1998 to 2019
$6.5MMechanisms of Post-transcriptional Gene Regulation by RNA Binding ProteinsR35GM136426 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Douglas L Black · 2020 to 2026
$5.4MElucidating an Xist-dependent program of sexually dimorphic alternative splicing in the mammalian brainR01MH109166 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BLACK, DOUGLAS L, PLATH, KATHRIN · 2016 to 2020
$3.3MRNA regulation of intrinsically-determined neuronal propertiesR01MH116220 · NIMH · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI ZHENG, SIKA · 2018 to 2022
$2.4MThe Regulation and Function of Neuron-Specific Alternative SplicingR01NS104041 · NINDS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI ZHENG, SIKA · 2018 to 2022
$2.1MMechanisms of Alternative Splicing Regulation by Rbfox ProteinsR01GM114463 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BLACK, DOUGLAS L · 2016 to 2019
$1.7MMechanism of chromatin remodeling and gene silencing by the lncRNAs Xist and TsixR01GM115233 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PLATH, KATHRIN · 2015 to 2018
$1.6MEstablishing an imaging methodology to study developmentally-regulated chromatin changes during X-chromosome InactivationR03HD095086 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MARKAKI, GIOLANTA · 2018 to 2019
$156kFunctional Dissection of the Mechanism that Lead to Loss of Somatic Cell IdentityR03HD088380 · NICHD · UNIVERSITY OF FLORIDA · PI PAPP, BERNADETT · 2017 to 2018
$153kMechanisms of X Chromosome Silencing and Its Relation to PluripotencyF32GM103139 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PANDYA-JONES, AMY · 2012 to 2013
$68kHoward Hughes Medical InstituteNCI NIH HHS P30 CA016042NICHD NIH HHS R03 HD088380NICHD NIH HHS R03 HD095086NIGMS NIH HHS F32 GM103139NIGMS NIH HHS R01 GM049662NIGMS NIH HHS R01 GM114463NIGMS NIH HHS R01 GM115233NIGMS NIH HHS R35 GM136426NIMH NIH HHS R01 MH109166NIMH NIH HHS R01 MH116220NINDS NIH HHS R01 NS104041
Abstract
Nuclear compartments have diverse roles in regulating gene expression, yet the molecular forces and components that drive compartment formation remain largely unclear
Indexed as
Gene SilencingAnimalsCELF1 ProteinCell LineDNA-Binding ProteinsFemaleHeterogeneous-Nuclear RibonucleoproteinsHumansIn Situ Hybridization, FluorescenceMaleMiceNuclear Matrix-Associated ProteinsPolypyrimidine Tract-Binding ProteinRNA-Binding ProteinsRNA, Long NoncodingX Chromosome InactivationCELF1 ProteinCELF1 protein, mouseDNA-Binding ProteinsHeterogeneous-Nuclear Ribonucleoproteinsmatrin-3 protein, mouseNuclear Matrix-Associated ProteinsPolypyrimidine Tract-Binding ProteinPtbp1 protein, mouseRNA-Binding ProteinsRNA, Long NoncodingTardbp protein, mouseXIST non-coding RNA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.