Evidence map›Paper›PMID 32908199›Full record

ArticleScientific reports2020

Parallel assessment of albuminuria and plasma sTNFR1 in people with type 2 diabetes and advanced chronic kidney disease provides accurate prognostication of the risks of renal decline and death.

William P Martin, Colm Tuohy, Alison Doody, Sabrina Jackson, Ronan J Canavan, David Slattery, Patrick J Twomey, Malachi J McKenna, Carel W le Roux, Neil G Docherty

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Biomarkers of Kidney Failure and All-Cause Mortality in CKD.Journal of the American Society of Nephrology : JASN · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Plasma Soluble Tumor Necrosis Factor Receptor Concentrations and Clinical Events After Hospitalization: Findings From the ASSESS-AKI and ARID Studies.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  6. Article
  7. Diabetes, Albuminuria and the Kidney-Brain Axis.Journal of clinical medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

William P MartinDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
Colm TuohyDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
Alison DoodyDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
Sabrina JacksonDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
Ronan J CanavanDepartment of Endocrinology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
David SlatteryDepartment of Endocrinology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Patrick J TwomeyDepartment of Clinical Chemistry, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Malachi J McKennaDepartment of Endocrinology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Carel W le RouxDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
Neil G DochertyDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland. neil.docherty@ucd.ie.
St. Vincent's University Hospital · IEUniversity College Dublin · IEImperial College London · GBUniversity of Gothenburg · SE

Funding

Wellcome TrustWellcome Trust 203930/B/16/Z
6 · The paper itself

Abstract

Identification of people with diabetes and chronic kidney disease at high-risk of early mortality is a priority to guide intensification of therapy. We aimed to investigate the complementary prognostic value of baseline urine albumin-to-creatinine ratio (uACR) and plasma soluble tumour necrosis factor receptor-1 (sTNFR1) with respect to early mortality and renal functional decline in a population with type 2 diabetes and advanced chronic kidney disease. We measured plasma sTNFR1 in people with type 2 diabetes (HbA

Indexed as

AlbuminuriaAgedAged, 80 and overBiomarkersCreatinineDiabetes Mellitus, Type 2Disease ProgressionFemaleHumansIrelandKidneyLongitudinal StudiesMaleMiddle AgedPrognosisReceptors, Tumor Necrosis Factor, Type IBiomarkersCreatinineReceptors, Tumor Necrosis Factor, Type ITNFRSF1A protein, human

Identifiers

PMID32908199
PMCPMC7481247
OpenAlexW3084406279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.