Evidence map›Paper›PMID 32908114›Full record

ArticleJournal of atherosclerosis and thrombosis2021

Effect of Target Lesion Revascularization on Restenosis Lesions of the Superficial Femoral Artery without Recurred Symptoms after Endovascular Therapy.

Makoto Utsunomiya, Mitsuyoshi Takahara, Masahiko Fujihara, Tatsuya Shiraki, Amane Kozuki, Masashi Fukunaga, Michinao Tan, Ryo Yoshioka, Yusuke Tomoi, Shinsuke Mori and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Percutaneous transluminal angioplasty with stenting for the treatment of lower limb arteriosclerosis obliterans.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Makoto UtsunomiyaDivision of Cardiovascular Medicine, Toho University Ohashi Medical Center.
Mitsuyoshi TakaharaDepartment of Metabolic Medicine and 2 Department of Diabetes Care Medicine, Osaka University Graduate School of Medicine.
Masahiko FujiharaCardiovascular Medicine, Kishiwada Tokushukai Hospital.
Tatsuya ShirakiCardiovascular Medicine, Osaka University.
Amane KozukiCardiovascular Medicine, Osaka Saiseikai Nakatsu Hospital.
Masashi FukunagaCardiovascular Medicine, Morinomiya Hospital.
Michinao TanCardivascular Center, Tokeidai Memorial Hospital.
Ryo YoshiokaCardiovascular Center, Sakakibara Hospital.
Yusuke TomoiCardiovascular Medicine, Kokura Memorial Hospital.
Shinsuke MoriCardiovascular Medicine, Yokohama Saiseikai Tobu Hospital.
Yusuke IwasakiCardiovascular Medicine, Osaka General Medical Center.
Shinya SasakiCardiovascular Medicine, Saka General Hospital.
Masato NakamuraDivision of Cardiovascular Medicine, Toho University Ohashi Medical Center.
Osaka University · JPToho University Ohashi Medical Center · JPKishiwada Tokushukai Hospital · JPKokura Memorial Hospital · JPMorinomiya Hospital · JPOsaka City General Hospital · JPSaiseikai Nakatsu Hospital · JPSakakibara Hospital · JPShowa General Hospital · JPTokeidai Memorial Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aims to elucidate the effects of early application of target lesion revascularization (TLR) to restenosis lesions of the superficial femoral artery (SFA) without recurrence of symptoms. Despite recent improvements in endovascular therapy (EVT) for the SFA, restenosis remains to be a problem. However, restenosis is not always associated with the recurrence of limb symptoms. Although early application of TLR is not generally approved for restenosis lesions of the SFA without recurred symptoms, it is expected to contribute to long-term patency and other favorable outcomes. Nonetheless, its effectiveness remains to be determined.

methodsWe retrospectively analyzed 616 patients who developed restenosis after undergoing femoro-popliteal EVT for claudication (Rutherford category 1 to 3) due to de novo femoro-popliteal lesions between January 2010 and December 2016 at 11 centers in Japan. Recurred symptoms were defined as symptoms of the same or higher Rutherford categories than those immediately before the initial EVT.

resultsOf the patients, 291 (47 %) lacked recurred symptoms; 69 (24 %) underwent TLR for restenosis. After propensity matching, the risk of occlusion was determined to be not significantly different between the TLR and observation groups; the 3-year occlusion-free rate was 68 % and 62 %, respectively (P=0.84). The risk of recurring symptoms, critical limb ischemia, and all-cause death was also found to be comparable between groups. The incidence of target vessel revascularization was significantly higher in the TLR than in the observation group (1.55 [95 % confidence interval: 1.25-1.93] vs. 0.59 [0.41-0.85] per 3 person-years).

conclusionsIn patients with SFA restenosis without recurred symptoms, early application of TLR showed no advantages.

Indexed as

Endovascular ProceduresFemoral ArteryIntermittent ClaudicationPeripheral Arterial DiseasePopliteal ArteryPostoperative ComplicationsReoperationAgedExtremitiesFemaleHumansJapanMaleOutcome and Process Assessment, Health CareRecurrenceRetrospective StudiesSuperficial femoral arteryTarget lesion revascularizationWithout symptom

Identifiers

PMID32908114
PMCPMC8219538
OpenAlexW3084379996

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.