Trial reportScience translational medicine2020
Therapeutic responses to
2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph
Trial report in Science translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 70 papers.
0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Metabolic Profiling of Immune Responses in Immune-Mediated Diseases
A Phase 2b, Double-Blind, Randomized, Placebo-Controlled Trial of Cardamom and Topical Roseomonas in Atopic Dermatitis
Who cites it
70 citing papers in PubMed, 121 citations in OpenAlex.
- Microbiological and clinical effects of probiotic-related Zeger therapy on gingival health: a randomized controlled clinical trial.BMC oral health · 2024Trial
- A Randomized, Double-Blind, Placebo-Controlled, Multicenter, 16-Week Trial to Evaluate the Efficacy and Safety of FB-401 in Children, Adolescents, and Adult Subjects (Ages 2 Years and Older) with Mild-to-Moderate Atopic Dermatitis.Dermatology (Basel, Switzerland) · 2024Trial
- Differential responses to folic acid in an established keloid fibroblast cell line are mediated by JAK1/2 and STAT3.PloS one · 2021Trial
- A Microbial Formulation Perspective on Probiotic Skincare: Viability, Challenges, and Current Approaches to Maintain Probiotic Viability.Biotechnology and bioengineering · 2026Review
- mSphere of Influence: Understanding atopic disease through the dynamics of skin-microbe interactions.mSphere · 2026Article
- Understanding Infantile Atopic Dermatitis: A Review of Environmental, Familial, Genetic and Microbial Influences.Current allergy and asthma reports · 2026Review
- Companion Dogs and Cats as Key Reservoirs of Antimicrobial Resistance: Evidence and One Health Implications.Antibiotics (Basel, Switzerland) · 2026Review
- Human and Marine Host Defense Peptides for Healthy Skin.Marine drugs · 2026Review
- Host-Candida auris interactions in the skin.PLoS pathogens · 2026Review
- Extracellular wax ester biosynthesis by staphylococcal lipases detoxifies skin fatty acids and shapes interspecies competition.The ISME journal · 2026Article
- Unlocking the therapeutic potential of sphingolipids in wound healing: from molecular mechanisms to clinical applications.International journal of surgery (London, England) · 2026Review
- A systemic epithelial-immune-neural framework for pediatric atopic dermatitis-allergic rhinitis comorbidity.Frontiers in immunology · 2026Article
- Dynamic remodeling of skin microbiota during healthy homeostatic and wound repair conditions.Frontiers in microbiology · 2026Review
- Emerging Microbiome-Based Therapies for Skin Infections: From Probiotics and Prebiotics to Synthetic Microbiome Engineering.Infection and drug resistance · 2026Review
- The human skin microbiome: from metagenomes to therapeutics.Nature reviews. Microbiology · 2025Review
- The Skin Microbiome and Bioactive Compounds: Mechanisms of Modulation, Dysbiosis, and Dermatological Implications.Molecules (Basel, Switzerland) · 2025Review
- The skin microbiome in dermatologic disease.Journal of the American Academy of Dermatology · 2025Review
- Microbiome-Based Products: Therapeutic Potential for Inflammatory Skin Diseases.International journal of molecular sciences · 2025Review
- Advancing Therapeutic Strategies in Atopic Dermatitis: Emerging Targets and Personalized Approaches.Biomolecules · 2025Review
- Tissue-Resident Memory and Follicular/Peripheral Helper PD-1European journal of immunology · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 8 institutions in 1 country.
Ian A MylesEpithelial Therapeutics Unit, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA. mylesi@niaid.nih.gov.ORCID 0000-0001-9316-3703
Carlo R CastilloEpithelial Therapeutics Unit, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1824-6696
Kent D BarbianRTS Genomics Unit, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA.ORCID 0000-0001-9861-6150
Kishore KanakabandiRTS Genomics Unit, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA.ORCID 0000-0003-3259-4459
Kimmo VirtanevaRTS Genomics Unit, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA.ORCID 0000-0002-5503-1483
Emily FitzmeyerRTS Genomics Unit, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA.ORCID 0000-0002-3962-190X
Monica PaneruRTS Genomics Unit, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA.
Francisco Otaizo-CarrasqueroGenomic Technologies Section, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0001-7518-173X
Timothy G MyersGenomic Technologies Section, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0002-7059-5906
Tovah E MarkowitzNIAID Collaborative Bioinformatics Resource (NCBR), NIAID, NIH, Bethesda, MD, USA.
Ian N MooreInfectious Disease Pathogenesis Section, Comparative Medicine Branch, NIAID, NIH, Rockville, MD, USA.ORCID 0000-0002-0391-6466
Xue LiuDepartment of Pre-clinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD, USA.ORCID 0000-0002-0431-490X
Marc FerrerDepartment of Pre-clinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD, USA.
Yosuke SakamachiNational Institute of Environmental Health Sciences, Research Triangle, NC, USA.
Stavros GarantziotisNational Institute of Environmental Health Sciences, Research Triangle, NC, USA.ORCID 0000-0003-4007-375X
Muthulekha SwamydasFungal Pathogenesis Section, LCIM, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0002-8665-7016
Michail S LionakisFungal Pathogenesis Section, LCIM, NIAID, NIH, Bethesda, MD, USA.
Erik D AndersonLaboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0001-5329-4629
Noah J EarlandLaboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0003-0170-407X
Sundar GanesanBiological Imaging Section, Research Technology Branch, NIAID, NIH, Bethesda, MD, USA.
Ashleigh A SunLaboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0003-3216-810X
Jenna R E BergersonLaboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.
Robert A SilvermanDepartment of Pediatrics, Georgetown University Hospital, Washington, DC, USA.ORCID 0000-0003-0674-4484
Maureen PetersenWalter Reed National Military Medical Center, Bethesda, MD, USA.ORCID 0000-0003-1885-4664
Craig A MartensRTS Genomics Unit, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA.
Sandip K DattaLaboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0003-0243-7815
National Institutes of Health · USRocky Mountain Institute · USNational Center for Advancing Translational Sciences · USNational Human Genome Research Institute · USTriangle · USFrederick National Laboratory for Cancer Research · USGeorgetown University · USWalter Reed National Military Medical Center · US
Funding
The Role of Hyaluronan And Inter-Alpha-Trypsin Inhibitor in Tissue InjuryZIAES102605 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GARANTZIOTIS, STAVROS · 2009 to 2025
$22.6MHost Immunity Against BacteriaZIAAI001043 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MYLES, IAN · 2009 to 2025
$18.9MIntramural NIH HHS ZIA AI001043Intramural NIH HHS ZIA AI001205Intramural NIH HHS ZIA ES102605
Abstract
Dysbiosis of the skin microbiota is increasingly implicated as a contributor to the pathogenesis of atopic dermatitis (AD). We previously reported first-in-human safety and clinical activity results from topical application of the commensal skin bacterium
Indexed as
Dermatitis, AtopicEczemaMethylobacteriaceaeAdultChildHumansLipidsSkinLipids
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT04864886ClinicalTrials.gov
NCT06096857ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.