Evidence map›Paper›PMID 32907950›Full record

ArticlemSphere2020

Binding of Leishmania infantum Lipophosphoglycan to the Midgut Is Not Sufficient To Define Vector Competence in

Iliano V Coutinho-Abreu, James Oristian, Waldionê de Castro, Timothy R Wilson, Claudio Meneses, Rodrigo P Soares, Valéria M Borges, Albert Descoteaux, Shaden Kamhawi, Jesus G Valenzuela

Abstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Review
  3. Phenotypical Differences betweenPathogens (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Iliano V Coutinho-AbreuVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA vieiracoutinhi2@niaid.nih.gov skamhawi@niaid.nih.gov jvalenzuela@niaid.nih.gov.ORCID 0000-0002-1389-1071
James OristianVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA.
Waldionê de CastroVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA.
Timothy R WilsonVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA.
Claudio MenesesVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA.
Rodrigo P SoaresFundação Oswaldo Cruz-FIOCRUZ, Instituto René Rachou, Belo Horizonte, MG, Brazil.
Valéria M BorgesFundação Oswaldo Cruz-FIOCRUZ, Instituto Gonçalo Moniz, Salvador, BA, Brazil.
Albert DescoteauxINRS-Centre Armand-Frappier Santé Biotechnologie, Laval, Quebec, Canada.
Shaden KamhawiVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA vieiracoutinhi2@niaid.nih.gov skamhawi@niaid.nih.gov jvalenzuela@niaid.nih.gov.
Jesus G ValenzuelaVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA vieiracoutinhi2@niaid.nih.gov skamhawi@niaid.nih.gov jvalenzuela@niaid.nih.gov.ORCID 0000-0002-5589-9450

Funding

Molecular approaches to understand vector-host and vector-pathogen interactionsZ01AI000932 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI VALENZUELA, JESUS · 2003 to 2008
$1.9M
Intramural NIH HHS Z01 AI000932
6 · The paper itself

Abstract

The major surface lipophosphoglycan (LPG) of

Indexed as

AnimalsDigestive SystemGlycosphingolipidsInsect VectorsLeishmania infantumPsychodidaeGlycosphingolipidslipophosphonoglycanLeishmaniaLPGparasite bindingparasite survivalsand flysand fly midgutvector competence

Identifiers

PMID32907950
PMCPMC7485685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.