Evidence map›Paper›PMID 32907862›Full record

ArticleBMJ case reports2020

Oxaliplatin-associated sarcoid-like reaction masquerading as recurrent colon cancer.

Surya Kiran Aedma, Anusha Chidharla, Sarah Kelting, Anup Kasi

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Surya Kiran AedmaInternal Medicine, Carle Foundation Hospital, Urbana, Illinois, USA.
Anusha ChidharlaInternal Medicine, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA.
Sarah KeltingMedical Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Anup KasiMedical Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA anupdoc@gmail.com.ORCID http://orcid.org/0000-0002-4305-5701
University of Kansas Medical Center · USCarle Foundation Hospital · USIllinois College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 54-year-old man with stage IV B metastatic colorectal cancer with liver and peritoneal metastasis was treated with cytoreductive surgery (extended left colectomy, right partial hepatectomy, resection of right diaphragm nodule) and perioperative oxaliplatin-based chemotherapy. The patient was cancer-free for 6 months, at which point a surveillance positron emission tomography-CT scan showed metabolically active hepatosplenic lesions and mediastinal and bilateral hilar lymph nodes. An endobronchial ultrasound bronchoscopy-guided fine needle aspiration of the mediastinal and hilar lymph nodes revealed non-necrotising granulomas. The workup was negative for bacterial, fungal or mycobacterial infection, cancer or autoimmune disease. Carcinoembryonic antigen and COLVERA (a circulating tumour DNA liquid biopsy test for the detection of recurrent colon cancer) tests were negative. Subsequently the rare diagnosis of a sarcoidosis-like reaction from oxaliplatin-based chemotherapy was made. Repeat imaging after 3 months showed resolution of the hepatosplenic lesions and lymphadenopathy, alike.

Indexed as

AdenocarcinomaAntineoplastic Combined Chemotherapy ProtocolsCarcinoembryonic AntigenChemotherapy, AdjuvantCholecystectomyCirculating Tumor DNAColectomyColonic NeoplasmsDiagnosis, DifferentialEndoscopic Ultrasound-Guided Fine Needle AspirationGranulomaHepatectomyHumansLiverLymph NodesMaleCarcinoembryonic AntigenCirculating Tumor DNAOxaliplatincancer interventioncontraindications and precautionsoncology

Identifiers

PMID32907862
PMCPMC7481089
OpenAlexW3084069521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.