Evidence map›Paper›PMID 32907843›Full record

ReviewClinical cancer research : an official journal of the American Association for Cancer Research2021

Sebaceous Carcinoma Epidemiology and Genetics: Emerging Concepts and Clinical Implications for Screening, Prevention, and Treatment.

Michael R Sargen, Gabriel J Starrett, Eric A Engels, Elizabeth K Cahoon, Margaret A Tucker, Alisa M Goldstein

Abstract readReview
In one paragraph

Review in Clinical cancer research : an official journal of the American Association for Cancer Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Subcutaneous Cervical Mass in the Northern Tree Shrew (Tupaia belangeri).Journal of the American Association for Laboratory Animal Science : JAALAS · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Sebaceous Neoplasms.Diagnostics (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Article
  17. Solar UVR and Variations in Systemic Immune and Inflammation Markers.JID innovations : skin science from molecules to population health · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael R SargenClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, NCI, Rockville, Maryland. michael.sargen@nih.gov.ORCID 0000-0003-1039-2522
Gabriel J StarrettLaboratory of Cellular Oncology, Center for Cancer Research, NCI, Bethesda, Maryland.ORCID 0000-0001-5871-5306
Eric A EngelsInfections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, Rockville, Maryland.
Elizabeth K CahoonRadiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, Rockville, Maryland.ORCID 0000-0002-8028-0588
Margaret A TuckerHuman Genetics Program, Division of Cancer Epidemiology and Genetics, NCI, Rockville, Maryland.ORCID 0000-0003-0274-6773
Alisa M GoldsteinClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, NCI, Rockville, Maryland.ORCID 0000-0002-7538-3582

Funding

Biology of Virus-associated CancersZIABC011894 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI STARRETT, GABRIEL · 2019 to 2025
$5.4M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Sebaceous carcinoma is an aggressive skin cancer with a 5-year overall survival rate of 78% for localized/regional disease and 50% for metastatic disease. The incidence of this cancer has been increasing in the United States for several decades, but the underlying reasons for this increase are unclear. In this article, we review the epidemiology and genetics of sebaceous carcinoma, including recent population data and tumor genomic analyses that provide new insights into underlying tumor biology. We further discuss emerging evidence of a possible viral etiology for this cancer. Finally, we review the clinical implications of recent advances in sebaceous carcinoma research for screening, prevention, and treatment.

Indexed as

Early Detection of CancerGenomicsHumansIncidenceMicrosatellite InstabilityRisk FactorsSebaceous Gland NeoplasmsSEER ProgramSkin NeoplasmsUnited States

Identifiers

PMID32907843
PMCPMC7854832

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.