Evidence map›Paper›PMID 32907815›Full record

ArticleDiabetes2020

Patrolling Monocytes Are Recruited and Activated by Diabetes to Protect Retinal Microvessels.

Francesco Tecilazich, Toan A Phan, Fabio Simeoni, Giulia Maria Scotti, Zeina Dagher, Mara Lorenzi

Open access · greenAbstract read
In one paragraph

Article in Diabetes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Mass cytometric analysis of circulating monocyte subsets in a murine model of diabetic gastroparesis.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
  3. Monocytes in Retinal Degeneration: Little Cells with a Big Impact.Advances in experimental medicine and biology · 2025
    Review
  4. Macrophage activation contributes to diabetic retinopathy.Journal of molecular medicine (Berlin, Germany) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Francesco TecilazichSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA francescotecilazich@gmail.com.
Toan A PhanSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA.ORCID 0000-0001-7998-3190
Fabio SimeoniCenter for Translational Genomics and Bioinformatics, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, Milan, Italy.
Giulia Maria ScottiCenter for Translational Genomics and Bioinformatics, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, Milan, Italy.
Zeina DagherSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA.
Mara LorenziSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA.
Massachusetts Eye and Ear Infirmary · USIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

VISION RESEARCHP30EY003790 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI Patricia Ann D'Amore · 1985 to 2026
$25.5M
Protection and Repair of Retinal MicrovesselsR21EY024108 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI LORENZI, MARA · 2014 to 2015
$537k
NEI NIH HHS P30 EY003790NEI NIH HHS R21 EY024108
6 · The paper itself

Abstract

In diabetes there is a long latency between the onset of hyperglycemia and the appearance of structural microangiopathy. Because Ly6C

Indexed as

AnimalsDiabetes Mellitus, ExperimentalDiabetic RetinopathyGene Expression RegulationMiceMice, KnockoutMonocytesNuclear Receptor Subfamily 4, Group A, Member 1Retinal VesselsNr4a1 protein, mouseNuclear Receptor Subfamily 4, Group A, Member 1

Identifiers

PMID32907815
PMCPMC7679768
OpenAlexW3086771901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.