Evidence map›Paper›PMID 32907609›Full record

ArticleJournal of orthopaedic surgery and research2020

Preincubation with a low-dose hydrogen peroxide enhances anti-oxidative stress ability of BMSCs.

Lei Wang, Fei Zhang, Wuxun Peng, Jian Zhang, Wentao Dong, Dajiang Yuan, Zhenwen Wang, Yinggang Zheng

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Role of NF-κB signaling pathway in HIn vitro cellular & developmental biology. Animal · 2024
    Article
  5. Article
  6. Propofol Induces the Expression of Nrf2 and HO-1 inTropical medicine and infectious disease · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Mesenchymal stem cell-derived exosomes for gastrointestinal cancer.World journal of gastrointestinal oncology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei WangDepartment of Orthopedics, The Affliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Fei ZhangDepartment of Orthopedics, The Affliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Wuxun PengDepartment of Orthopedics, The Affliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China. pwx200228@aliyun.com.
Jian ZhangDepartment of Orthopedics, The Affliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China. pwx200228@aliyun.com.
Wentao DongDepartment of Orthopedics, The Affliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Dajiang YuanGuizhou Medical University, Guiyang, 550004, Guizhou, China.
Zhenwen WangGuizhou Medical University, Guiyang, 550004, Guizhou, China.
Yinggang ZhengGuizhou Medical University, Guiyang, 550004, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of low-concentration hydrogen peroxide pretreatment on the anti-oxidative stress of the bone marrow mesenchymal stem cells (BMSCs).

methodsRabbit BMSCs were isolated and cultured by density gradient centrifugation combined with the adherence method. Then, the third generation of well-grown BMSCs was continuously treated with 50-μM hydrogen peroxide (H

resultsA large number of typical BMSCs were obtained by density gradient centrifugation and adherent culture. The oxidative stress cell model was successfully established by 500-μM H

conclusionPretreatment with low-concentration H

Indexed as

AnimalsApoptosisCatalaseCell Culture TechniquesCells, CulturedCell SurvivalCentrifugation, Density GradientDose-Response Relationship, DrugHydrogen PeroxideMalondialdehydeMesenchymal Stem CellsOxidative StressRabbitsReactive Oxygen SpeciesSuperoxide DismutaseCatalaseHydrogen PeroxideMalondialdehydeReactive Oxygen SpeciesSuperoxide DismutaseBone marrow mesenchymal stem cellsHydrogen peroxide, ApoptosisOxidative stress injuryPretreatment

Identifiers

PMID32907609
PMCPMC7487789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.