Evidence map›Paper›PMID 32907378›Full record

ArticleCell transplantation

Comparison of Surgical and Cadaveric Intestine as a Source of Crypt Culture in Humans.

Andrew Scott, Barbara Olack, Joshua D Rouch, Hassan A Khalil, Brent A Kokubun, Nan Ye Lei, Jiafang Wang, Sergio Solorzano, Michael Lewis, James C Y Dunn and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Andrew ScottDepartment of Surgery, David Geffen School of Medicine, 12222UCLA, Los Angeles, CA, USA.
Barbara OlackDepartment of Diabetes and Cancer Discovery Science, 20220City of Hope, Integrated Islet Distribution Program and Intestinal Stem Cell Consortium, Coordinating Center, Duarte, CA, USA.
Joshua D RouchDepartment of Surgery, David Geffen School of Medicine, 12222UCLA, Los Angeles, CA, USA.
Hassan A KhalilDepartment of Surgery, David Geffen School of Medicine, 12222UCLA, Los Angeles, CA, USA.
Brent A KokubunDepartment of Surgery, David Geffen School of Medicine, 12222UCLA, Los Angeles, CA, USA.
Nan Ye LeiDepartment of Surgery, David Geffen School of Medicine, 12222UCLA, Los Angeles, CA, USA.
Jiafang WangDivision of Gastroenterology and Nutrition, Department of Pediatrics, Mattel Children's Hospital and the David Geffen School of Medicine, 12222UCLA Los Angeles, CA, USA.
Sergio SolorzanoDivision of Gastroenterology and Nutrition, Department of Pediatrics, Mattel Children's Hospital and the David Geffen School of Medicine, 12222UCLA Los Angeles, CA, USA.
Michael LewisDepartment of Pathology, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
James C Y DunnDepartment of Surgery, 6429Stanford University School of Medicine, Stanford, CA, USA.
Matthias G StelznerDepartment of Surgery, David Geffen School of Medicine, 12222UCLA, Los Angeles, CA, USA.
Joyce C NilandDepartment of Diabetes and Cancer Discovery Science, 20220City of Hope, Integrated Islet Distribution Program and Intestinal Stem Cell Consortium, Coordinating Center, Duarte, CA, USA.
Martín G MartínDivision of Gastroenterology and Nutrition, Department of Pediatrics, Mattel Children's Hospital and the David Geffen School of Medicine, 12222UCLA Los Angeles, CA, USA.ORCID 0000-0002-7192-0504
University of California, Los Angeles · USMattel Children's Hospital · USCity of Hope · USStanford University · USVA Greater Los Angeles Healthcare System · US

Funding

The Human Islet Distribution Coordinating Center (UC4)UC4DK098085 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI EVANS-MOLINA, CARMELLA, NILAND, JOYCE CAROL · 2012 to 2017
$25.6M
Pilot and Feasibility ProgramP30DK041301 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROZENGURT, JUAN ENRIQUE · 1990 to 2019
$18.0M
Integrated Islet Distribution Program (U24) - 2021U24DK098085 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI Carmella Evans-Molina, Joyce Carol Niland · 2021 to 2026
$17.8M
COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepositoryRC2DK118640 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI James Richard Goldenring, Izumi Kaji · 2019 to 2026
$14.8M
Intestinal Stem Cell Consortium Coordinating CenterU01DK085532 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NILAND, JOYCE CAROL · 2009 to 2018
$6.5M
Intestinal Stem Cell Culture and Entero-Endocrine Lineage DevelopmentU01DK085535 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUNN, JAMES C, MARTIN, MARTIN G · 2009 to 2018
$3.7M
Limited Competition for the Continuation of the Intestinal Stem Cell Consortium Coordinating CenterU24DK085532 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NILAND, JOYCE CAROL · 2019 to 2023
$2.3M
NIDDK NIH HHS P30 DK041301NIDDK NIH HHS RC2 DK118640NIDDK NIH HHS U01 DK085532NIDDK NIH HHS U01 DK085535NIDDK NIH HHS U24 DK085532NIDDK NIH HHS U24 DK098085NIDDK NIH HHS UC4 DK098085
6 · The paper itself

Abstract

Human small intestinal crypts are the source of intestinal stem cells (ISCs) that are capable of undergoing self-renewal and differentiation to an epithelial layer. The development of methods to expand the ISCs has provided opportunities to model human intestinal epithelial disorders. Human crypt samples are usually obtained from either endoscopic or discarded surgical samples, and are thereby exposed to warm ischemia, which may impair their

Indexed as

CadaverCell Culture TechniquesCell DifferentiationHumansIntestinescadavericintestinal stem cellssurgical

Identifiers

PMID32907378
PMCPMC7784595
OpenAlexW3086677855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.